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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 26 — Dec. 24, 2007
  • pp: 17891–17901

Enhancement of fluorescence-based sensing using microstructured optical fibres

V. Shahraam Afshar, Stephen C. Warren-Smith, and Tanya M. Monro  »View Author Affiliations

Optics Express, Vol. 15, Issue 26, pp. 17891-17901 (2007)

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We develop a generic model of excitation and fluorescence recapturing within filled microstructured optical fibres (MOFs) with arbitrary structure and demonstrate that the light-matter overlap alone does not determine the optimal fibre choice. Fibre designs with sub-wavelength features and high-index glasses exhibit localised regions of high intensity, and we show that these regions can lead to approximately two orders of magnitude enhancement of fluorescence recapturing. Here we show how this regime can be exploited for sensing and demonstrate experimentally in-fibre excitation and fluorescence recapturing within a filled, solid-core MOF.

© 2007 Optical Society of America

OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(060.4005) Fiber optics and optical communications : Microstructured fibers

ToC Category:
Fiber Optics and Optical Communications

Original Manuscript: October 23, 2007
Revised Manuscript: December 12, 2007
Manuscript Accepted: December 12, 2007
Published: December 14, 2007

Shahraam Afshar V., Stephen C. Warren-Smith, and Tanya M. Monro, "Enhancement of fluorescence-based sensing using microstructured optical fibres," Opt. Express 15, 17891-17901 (2007)

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  1. G. Stewart and B. Culshaw, "Optical Waveguide Modelling and Design for Evanescent Field Chemical Sensors," Opt. Quantum Electron. 26, s249 (1994). [CrossRef]
  2. J. B. Jensen, P. E. Hoiby, G. Emiliyanov, O. Bang, L. H. Pedersen, and A. Bjarklev, "Selective Detection of Antibodies in Microstructured Polymer Optical Fibers," Opt. Express 13, 5883-5889 (2005). [CrossRef] [PubMed]
  3. S. O. Konorov, A. M. Zheltikov, and M. Scalora, "Photonic-Crystal Fiber as a Multifunctional Optical Sensor and Sample Collector," Opt. Express 13, 3454-3459 (2005). [CrossRef] [PubMed]
  4. L. Rindorf, P. E. Hoiby, J. B. Jensen, L. H. Pedersen, O. Bang, and O. Geschke, "Towards Biochips Using Microstructured Optical Fiber Sensors," Anal. Bioanal. Chem. 385, 1370-1375 (2006). [CrossRef] [PubMed]
  5. C. M. B. Cordeiro, M. A. R. Franco, G. Chesini, E. C. S. Barretto, R. Lwin, C. H. B. Cruz, and M. C. J. Large, "Microstructured-Core Optical Fibre for Evanescent Sensing Applications," Opt. Express 14, 13,056-13,066 (2006). [CrossRef]
  6. F. Warken, E. Vetsch, D. Meachede, M. Sokolowski, and A. Rauschenbeutel, "Ultra-Sensitive Surface Absorption Spectroscopy Using Sub-Wavelength Diameter Optical Fibers," Opt. Express 15, 11,952-11,958 (2007). [CrossRef]
  7. S. Smolka, M. Barth, and O. Benson, "Highly Efficient Fluorescence Sensing with Hollow Core Photonic Crystal Fibers," Opt. Express 15, 12,783 (2007). [CrossRef]
  8. W. Henry, "Evanescent Field Devices: A Comparison Between Tapered Optical Fibres and Polished or D-Fibres," Opt. Quantum Electron. 26, s261-s272 (1994). [CrossRef]
  9. P. Lucas, M. R. Riley, C. Boussard-Pledel, and B. Bureau, "Advances in Chalcogenide Fiber Evanescent Wave Biochemical Sensing," Anal. Biochem. 351, 1-10 (2006). [CrossRef]
  10. Q1. G. Stewart, W. Jin, and B. Culshaw, "Prospects for Fibre-Optic Evanescent-Field Gas Sensors Using Absorption in the Near-Infrared," Sens. Actuators B 38-39, 42-47 (1997). [CrossRef]
  11. J. Lou, L. Tong, and Z. Ye, "Modeling of Silica Nanowires for Optical Sensing," Opt. Express 13, 2135-2140 (2005). [CrossRef] [PubMed]
  12. Y. Zhu, H. Du, and R. Bise, "Design of Solid-Core Microstructured Optical Fiber with Steering-Wheel Air Cladding for Optimal Evanescent-Field Sensing," Opt. Express 14, 3541-3546 (2006). [CrossRef] [PubMed]
  13. J. B. Jensen, L. H. Pedersen, P. E. Hoiby, L. B. Nielsen, T. P. Hansen, J. R. Folkenberg, J. Riishede, D. Noordegraaf, K. Nielsen, A. Carlsen, and A. Bjarklev, "Photonic Crystal Fiber Based Evanescent-Wave Sensor for Detection of Biomolecules in Aqueous Solutions," Opt. Lett. 29, 1974-1976 (2004). [CrossRef] [PubMed]
  14. Y. K. Lize, E. Magi, V. Taeed, J. Bolger, P. Steinvurzel, and B. Eggleton, "Microstructured Optical Fiber Photonic Wires with Subwavelength Core Diameter," Opt. Express 12, 3209-3217 (2004). [CrossRef] [PubMed]
  15. K. J. Rowland, S. Afshar V., and T. M. Monro, "Nonlinearity Enhancement of Filled Microstructured Fibers Operating in Nanowire Regime," in Proceedings of OFC 2006, p. OTuH3 (2006).
  16. L. Tong, J. Lou, and E. Mazur, "Single-Mode Guiding Properties of Subwavelength-Diameter Silica and Silicon Wire Waveguides," Opt. Express 12, 1025-1035 (2004). [CrossRef] [PubMed]
  17. S. Smolka, M. Barth, and O. Benson, "Selectively Coated Photonic Crystal Fiber for Highly Sensitive Fluorescence Detection," Appl. Phys. Lett. 90, 111,101 (2007). [CrossRef]
  18. Z. Liu and J. Pawliszyn, "Capillary Isoelectric Focusing of Proteins with Liquid Core Waveguide Laser-Induced Fluorescence Whole Column Imaging Detection," Anal. Chem. 75, 4887-4894 (2003). [CrossRef] [PubMed]
  19. Y. Huang, Y. Xu, and A. Yariv, "Fabrication of Functional Microstructured Optical Fibers Through a Selective- Filling Technique," Appl. Phys. Lett. 85, 5182 (2004). [CrossRef]
  20. T. Ritari, J. Tuominen, H. Ludvigsen, J. Petersen, T. Sorensen, T. Hansen, and H. Simonsen, "Gas Sensing Using Air-Guiding Photonic Bandgap Fibers," Opt. Express 12, 4080 (2004). [CrossRef] [PubMed]
  21. H. P. Kao, N. Yang, and J. S. Schoeniger, "Enhancement of Evanescent Fluorescence from Fiber-Optic Sensors by Thin-Film Sol-Gel Coating," J. Opt. Soc. Am. A 15, 21632,170 (1998).
  22. M. Nagel, A. Marchewka, and H. Kurz, "Low-Index Discontinuity Terahertz Waveguides," Opt. Express 14, 9944 (2006). [CrossRef] [PubMed]
  23. Q2. G. S. Wiederhecker, C. M. B. Cordeiro, F. Couny, F. Benabid, S. A. Maier, J. C. Knight, C. H. B. Cruz, and H. L. Fragnito, "Field Enhancement Within an Optical Fibre with a Subwavelength Air Core," Nature Photonics 1, 115 (2007). [CrossRef]
  24. N. Ganesh and B. T. Cunningham, "Photonic Crystal Enhanced Fluorescence," in Technical Digest, p. CThz5 (Optical Society of America, 2007).
  25. V. R. Almeida, Q. Xu, C. A. Barrios, and M. Lipson, "Guiding and Confining Light in Void Nanostructure," Opt. Lett. 29, 1209-1211 (2004). [CrossRef] [PubMed]
  26. R. E. Bailey, A. M. Smith, and S. Nie, "Quantum Dots in Biology and Medicine," Physica E 25, 1-12 (2004). [CrossRef]
  27. A. W. Snyder and J. D. Love, Optical Waveguide Theory (Chapman and hall, 2-6 Boundary Row, London SE1 8HN, UK, 1995).
  28. F. W. D. Rost, Fluorescence Microscopy (Cambridge University Press, Cambridge, UK, 1992).
  29. D. Marcuse, "Launching Light Into Fiber Cores from Sources Located in the Cladding," J. Lightwave Technol. 6, 1273-1279 (1988). [CrossRef]
  30. H. Ebendorff-Heidepriem, P. Petropoulos, S. Asimakis, V. Finazzi, R. C. Moore, K. Frampton, F. Koizumi, D. J. Richardson, and T. M. Monro, "Bismuth Glass Holey Fibers with High Nonlinearity," Opt. Express 12, 5082-87 (2004). [CrossRef] [PubMed]
  31. C. M. B. Cordeiro, M. A. R. Franco, C. J. S. Matos, F. Sircilli, V. A. Serrao, and C. H. B. Cruz, "Single-Design- Parameter Microstructured Optical Fiber for Chromatic Dispersion Tailoring and Evanescent Field Enhancement," Opt. Lett. 32, 3324-26 (2007). [CrossRef] [PubMed]
  32. A. Zheltikov, "Gaussian-Mode Analysis of Waveguide-Enhanced Kerr-Type Nonlinearity of Optical Fibers and Photonic Wires," J. Opt. Soc. Am. B 22, 1100-1104 (2005). [CrossRef]
  33. P. Agrawal, Nonlinear Fiber Optics. Academic press, Burlington, (2007).
  34. E. W. Washburn, "The Dynamics of Capillary Flow," Physical Review 17, 273-283 (1921). [CrossRef]
  35. I. B. Berlman, Handbook of fluorescence spectra of aromatic molecules (Academic Press, New York, 1971).
  36. E. Schartner, Y. Ruan, P. Hoffman, and T. M. Monro, "An Optical Fibre Protein Sensor," in COIN-ACOFT 2007 Proceeding, pp. WeB1-3 (Australian Optical Society, 2007).
  37. Y. Ruan, W. Li, R. Jarvis, N. Madsen, A. Rode, and B. Luther-Davies, " Fabrication and Characterization of Low Loss Rib Chalcogenide Waveguide Made by Dry Etching, " Opt. Express 12, 5140-5145(2004). [CrossRef] [PubMed]
  38. H. Ebendorff-Heidepriem, Y. Li, and T. M. Monro, "Reduced Loss in Extruded Microstructured Optical Fiber," Electron. Lett.,  43, 1343-1345(2007). [CrossRef]

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