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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 5 — Mar. 5, 2007
  • pp: 2432–2444

Spectral-domain spectrally-encoded endoscopy

Dvir Yelin, W. Matthew White, Jason. T. Motz, Seok H. Yun, Brett E. Bouma, and Guillermo J. Tearney  »View Author Affiliations


Optics Express, Vol. 15, Issue 5, pp. 2432-2444 (2007)
http://dx.doi.org/10.1364/OE.15.002432


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Abstract

Spectrally-encoded miniature endoscopy uses a single optical fiber and wavelength division multiplexing to obtain macroscopic images through miniature, flexible probes. In turn, it has the potential to enable two- and three-dimensional imaging within the body at locations that are currently difficult to access with conventional endoscopes. Here we present a novel detection scheme for spectrally-encoded endoscopy using spectral-domain interferometry. Compared to previous time-domain configurations, this new detection method results in greater than 1000-fold increase in sensitivity (77 dB), a 6-fold increase in imaging speed (30 volumes per second), and a 2-fold increase in depth range (2.8 mm). We demonstrate spectrally-encoded, spectral-domain detection by conducting video-rate, three-dimensional imaging in a variety of specimens, including the paws of a mouse embryo and excised human ear bones. Our results show that this new technology enables video rate spectrally-encoded endoscopy and will therefore be useful for a variety of minimally invasive medical applications.

© 2007 Optical Society of America

OCIS Codes
(110.1650) Imaging systems : Coherence imaging
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: December 4, 2006
Revised Manuscript: January 12, 2007
Manuscript Accepted: January 17, 2007
Published: March 5, 2007

Virtual Issues
Vol. 2, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Dvir Yelin, W. M. White, Jason T. Motz, Seok H. Yun, Brett E. Bouma, and Guillermo J. Tearney, "Spectral-domain spectrally-encoded endoscopy," Opt. Express 15, 2432-2444 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-5-2432


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References

  1. B. I. Hirschowitz, "Endoscopic examination of the stomach and duodenal cap with the fiberscope," Lancet 1, 1074-1078 (1961). [CrossRef] [PubMed]
  2. F. Ishibashi, K. Aziz, G. S. Abela, and S. Waxman, "Update on Coronary Angioscopy: Review of a 20-year experience and potential application for detection of vulnerable plaque," J. Interven. Cardio. 19, 17-25 (2006). [CrossRef]
  3. V. R. Jacobs, M. Kiechle, B. Plattner, T. Fischer, and S. Paepke, "Breast ductoscopy with a 0.55-mm mini-endoscope for direct visualization of intraductal lesions," J Minim Invasive Gynecol 12, 359-364 (2005). [CrossRef] [PubMed]
  4. T. Matsunaga, Y. Kawakami, K. Namba, and M. Fujii, "Intraductal biopsy for diagnosis and treatment of intraductal lesions of the breast," Cancer 101, 2164-2169 (2004). [CrossRef] [PubMed]
  5. E. A. Reece, "First trimester prenatal diagnosis: Embryoscopy and fetoscopy," Sem. Perinat. 23, 424-433 (1999). [CrossRef]
  6. C. M. Brown, P. G. Reinhall, S. Karasawa, and E. J. Seibel, "Optomechanical design and fabrication of resonant microscanners for a scanning fiber endoscope," Opt. Eng. 45, 043001 (2006). [CrossRef]
  7. D. L. Dickensheets and G. S. Kino, "Micromachined scanning confocal optical microscope," Opt. Lett. 21, 764-766 (1996). [CrossRef] [PubMed]
  8. A. L. Polglase, W. J. McLaren, S. A. Skinner, R. Kiesslich, M. F. Neurath, and P. M. Delaney, "A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract," Gastro. Endosc. 62, 686-695 (2005). [CrossRef]
  9. G. J. Tearney, M. Shishkov, and B. E. Bouma, "Spectrally encoded miniature endoscopy," Opt. Lett. 27, 412-414 (2002). [CrossRef]
  10. G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. J. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21, 543-545 (1996). [CrossRef] [PubMed]
  11. D. Yelin, B. E. Bouma, N. Iftimia, and G. J. Tearney, "Three-dimensional spectrally encoded imaging," Opt. Lett. 28, 2321-2323 (2003). [CrossRef] [PubMed]
  12. L. Froehly, S. N. Martin, T. Lasser, C. Depeursinge, and F. Lang, "Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle," Opt. Commun. 222, 127-136 (2003). [CrossRef]
  13. D. Yelin, S. H. Yun, B. E. Bouma, and G. J. Tearney, "Three-dimensional imaging using spectral encoding heterodyne interferometry," Opt. Lett. 30, 1794-1796 (2005). [CrossRef] [PubMed]
  14. D. Yelin, I. Rizvi, W. M. White, J. T. Motz, T. Hasan, B. E. Bouma, and G. J. Tearney, "Three-dimensional miniature endoscopy," Nature 443, 765-765 (2006). [CrossRef] [PubMed]
  15. G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, "High-speed phase- and group-delay scanning with a grating-based phase control delay line," Opt. Lett. 22, 1811-1813 (1997). [CrossRef]
  16. M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, "Full range complex spectral optical coherence tomography technique in eye imaging," Opt. Lett. 27, 1415-1417 (2002). [CrossRef]
  17. C. Klug, B. Fabinyi, and M. Tschabitscher, "Endoscopy of the middle ear through the Eustachian tube: Anatomic possibilities and limitations," Am. J. Otol. 20, 299-303 (1999). [PubMed]
  18. O. D. Almeida, "Current state of office laparoscopic surgery," J. Am. Assoc. of Gynecol. Laparosc. 7, 545-546 (2000). [CrossRef]
  19. J. R. Feste, "Use of optical catheters for diagnostic office laparoscopy," J. Reprod. Med. 41, 307-312 (1996). [PubMed]
  20. P. N. Fuller, "Microendoscopic surgery: A comparison of four microendoscopes and a review of the literature," Am. J. Obstet. Gynecol. 174, 1757-1761 (1996). [CrossRef] [PubMed]
  21. O. Nahlieli and A. M. Baruchin, "Sialoendoscopy: three years' experience as a diagnostic and treatment modality," J Oral Maxillofac. Surg. 55, 912-918; discussion 919-920 (1997). [CrossRef] [PubMed]
  22. S. Rimbach, G. Bastert, and D. Wallwiener, "Technical results of falloposcopy for infertility diagnosis in a large multicentre study," Human Reprod. 16, 925-930 (2001). [CrossRef]
  23. N. Fujita, Y. Noda, G. Kobayashi, K. Kimura, and K. Ito, "Endoscopic approach to early diagnosis of pancreatic cancer," Pancreas 28, 279-281 (2004). [CrossRef] [PubMed]
  24. T. Philipp, W. Feichtinger, M. I. Van Allen, E. Separovic, A. Reiner, and D. K. Kalousek, "Abnormal embryonic development diagnosed embryoscopically in early intrauterine deaths after in vitro fertilization: a preliminary report of 23 cases," Fertil. Steril. 82, 1337-1342 (2004). [CrossRef] [PubMed]
  25. M. V. Senat, J. Deprest, M. Boulvain, A. Paupe, N. Winer, and Y. Ville, "Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndrome," New Eng. J. Med. 351, 136-144 (2004). [CrossRef] [PubMed]
  26. G. Cinalli, P. Cappabianca, R. de Falco, P. Spennato, E. Cianciulli, L. M. Cavallo, F. Esposito, C. Ruggiero, G. Maggi, and E. de Divitiis, "Current state and future development of intracranial neuroendoscopic surgery," Expert Rev. Med. Dev. 2, 351-373 (2005). [CrossRef]
  27. C. Schizas, E. Tsiridis, and J. Saksena, "Microendoscopic discectomy compared with standard microsurgical discectomy for treatment of uncontained or large contained disc herniations," Neurosurgery 57, 357-360; discussion 357 - 360 (2005). [CrossRef] [PubMed]
  28. A. J. Saltzman and S. Waxman, "Angioscopy and ischemic heart disease," Curr. Opin. Cardiol. 17, 633 - 637 (2002). [CrossRef] [PubMed]
  29. D. Yelin, B. E. Bouma, S. H. Yun, and G. J. Tearney, "Double-clad fiber for endoscopy," Opt. Lett. 29, 2408 - 2410 (2004). [CrossRef] [PubMed]
  30. J. T. Motz, D. Yelin, B. J. Vakoc, B. E. Bouma, and G. J. Tearney, "Spectral- and frequency-encoded fluorescence imaging," Opt. Lett. 30, 2760-2762 (2005). [CrossRef] [PubMed]

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