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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 5 — Mar. 5, 2007
  • pp: 2432–2444

Spectral-domain spectrally-encoded endoscopy

Dvir Yelin, W. Matthew White, Jason. T. Motz, Seok H. Yun, Brett E. Bouma, and Guillermo J. Tearney  »View Author Affiliations

Optics Express, Vol. 15, Issue 5, pp. 2432-2444 (2007)

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Spectrally-encoded miniature endoscopy uses a single optical fiber and wavelength division multiplexing to obtain macroscopic images through miniature, flexible probes. In turn, it has the potential to enable two- and three-dimensional imaging within the body at locations that are currently difficult to access with conventional endoscopes. Here we present a novel detection scheme for spectrally-encoded endoscopy using spectral-domain interferometry. Compared to previous time-domain configurations, this new detection method results in greater than 1000-fold increase in sensitivity (77 dB), a 6-fold increase in imaging speed (30 volumes per second), and a 2-fold increase in depth range (2.8 mm). We demonstrate spectrally-encoded, spectral-domain detection by conducting video-rate, three-dimensional imaging in a variety of specimens, including the paws of a mouse embryo and excised human ear bones. Our results show that this new technology enables video rate spectrally-encoded endoscopy and will therefore be useful for a variety of minimally invasive medical applications.

© 2007 Optical Society of America

OCIS Codes
(110.1650) Imaging systems : Coherence imaging
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: December 4, 2006
Revised Manuscript: January 12, 2007
Manuscript Accepted: January 17, 2007
Published: March 5, 2007

Virtual Issues
Vol. 2, Iss. 4 Virtual Journal for Biomedical Optics

Dvir Yelin, W. M. White, Jason T. Motz, Seok H. Yun, Brett E. Bouma, and Guillermo J. Tearney, "Spectral-domain spectrally-encoded endoscopy," Opt. Express 15, 2432-2444 (2007)

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