OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 13 — Jun. 23, 2008
  • pp: 9927–9935

Polarization-sensitive reflectance imaging in skeletal muscle

Xin Li, Janaka C. Ranasinghesagara, and Gang Yao  »View Author Affiliations


Optics Express, Vol. 16, Issue 13, pp. 9927-9935 (2008)
http://dx.doi.org/10.1364/OE.16.009927


View Full Text Article

Enhanced HTML    Acrobat PDF (307 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We acquired polarization-sensitive reflectance images in freshly excised skeletal muscle samples. The obtained raw images varied depending on the incident and detection polarization states. The Stokes vectors were measured for incident light of four different polarization states, and the whole Mueller matrix images were also calculated. We found that the images obtained in skeletal muscles exhibited different features from those obtained in a typical polystyrene sphere solution. The back-reflected light in muscle maintained a higher degree of polarization along the axis perpendicular to muscle fiber orientation. Our analysis indicates that the unique muscle sarcomere structure plays an important role in modulating the propagation of polarized light in whole muscle.

© 2008 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5280) Medical optics and biotechnology : Photon migration
(260.5430) Physical optics : Polarization
(290.1350) Scattering : Backscattering

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 28, 2008
Revised Manuscript: May 22, 2008
Manuscript Accepted: June 16, 2008
Published: June 20, 2008

Virtual Issues
Vol. 3, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Xin Li, Janaka C. Ranasinghesagara, and Gang Yao, "Polarization-sensitive reflectance imaging in skeletal muscle," Opt. Express 16, 9927-9935 (2008)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-13-9927


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. C. G. Bonnemann and N. G. Laing, "Myopathies resulting from mutations in sarcomeric proteins," Curr. Opin. Neurol. 17, 529-537 (2004). [CrossRef] [PubMed]
  2. R. L. Lieber and J. Fridén, "Implications of Muscle Design on Surgical Reconstruction of Upper Extremities," Clin. Orthop. 419, 267-279 (2004). [CrossRef] [PubMed]
  3. N. G. Laing and K. J. Nowak, "When contractile proteins go bad: the sarcomere and skeletal muscle disease," BioEssays 27, 809-822 (2005). [CrossRef] [PubMed]
  4. J. Xia, A. Weaver, D. E. Gerrard, and G. Yao, "Monitoring sarcomere structure changes in whole muscle using diffuse reflectance," J Biomed. Opt. 11, 040504 (2006). http://spiedl.aip.org/journals/doc/JBOPFO-ft/vol_11/iss_4/040504_1.html [CrossRef] [PubMed]
  5. J. Ranasinghesagara and G. Yao, "Imaging 2D optical diffuse reflectance in skeletal muscle," Opt. Express 15, 3998-4007 (2007). [CrossRef] [PubMed]
  6. V. Backman, R. Gurjar, K. Badizadegan, I. Itzkan, P. R. Dasari, L. T. Perelman, and M. S. Feld, "Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ," IEEE J. Quantum Electron. 5, 1019-1026 (1999) [CrossRef]
  7. G. Yao, "Differential optical polarization imaging in turbid media with different embedded objects," Opt. Commun. 241, 255-261 (2004). [CrossRef]
  8. T. M. Johnson and J. R. Mourant, "Polarized wavelength-dependent measurement of turbid media," Opt. Express 4, 200 (1999). [CrossRef] [PubMed]
  9. L. T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J. M. Crawford, and M. S. Feld, "Observation of periodic fine structure in reflectance from biological tissue: A new technique for measuring nuclear size distribution," Phys. Rev. Lett.,  80, 627 (1998). [CrossRef]
  10. K. Sokolov, R. Drezek, K. Gossagee, and R. Richards-Kortum, "Reflectance spectroscopy with polarized light: Is it sensitive to cellular and nuclear morphology," Opt. Express 5, 302 (1999). [CrossRef] [PubMed]
  11. S. L. Jiao, G. Yao, and L. H. V. Wang, "Depth-resolved two-dimensional Stokes vectors of backscattered light and Mueller matrices of biological tissue measured with optical coherence tomography," Appl. Opt. 39, 6318-6324 (2000). [CrossRef]
  12. C. E. Saxer, J. F. De Boer, B. H. Park, Y. H. Zhao, Z. P. Chen, and J. S. Nelson, "High-speed fiber-based polarization-sensitive optical coherence tomography of in vivo human skin," Opt. Lett. 25, 1355-1357 (2000). [CrossRef]
  13. R. E. Nothdurft and G. Yao, "Study of subsurface polarization imaging in turbid media with different embedded objects," Opt. Express 13, 4185-4195(2005). [CrossRef] [PubMed]
  14. R. E. Nothdurft and G. Yao, "Applying the polarization memory effect in polarization-gated subsurface imaging," Opt. Express 14, 4656-4661(2006). [CrossRef] [PubMed]
  15. R. E. Nothdurft and G. Yao, "Effects of turbid media optical properties on object visibility in subsurface polarization imaging," Appl. Opt. 45,5532-5541(2006). [CrossRef] [PubMed]
  16. P. J. Paolini, R. Sabbadini, K. P. Roos, and R. J. Baskin, "Sarcomere length dispersion in single muscle fibers and fiber bundles," Biophys. J. 16, 919-930 (1976). [CrossRef] [PubMed]
  17. J. S. Baba, J. R. Chung, A. H. DeLaughter, B. D. Cameron, and G. L. Cote, "Development and calibration of an automated Mueller matrix polarization imaging system," J. Biomed Opt 7, 341 (2002). [CrossRef] [PubMed]
  18. W. H. Press, B. R. Flannery, S. A. Teukolosky, and W. T. Vetterling, Numerical recipes in C: The Art of Scientific Computing, (Cambridge University Press, Cambridge, 1988).
  19. J. J. Pasquesi, S. C. Schlachter, M. D. Boppart, E. Chaney, S. J. Kaufman, and S. A. Boppart, "In vivo detection of exercised-induced ultrastructural changes in genetically-altered murine skeletal muscle using polarization-sensitive optical coherence tomography," Opt. Express 14, 1547-1556 (2006). [CrossRef] [PubMed]
  20. A. Hielscher, A. Eick, J. Mourant, D. Shen, J. Freyer, and I. Bigio, "Diffuse backscattering Mueller matricesof highly scattering media," Opt. Express 1, 441-453 (1997). [CrossRef] [PubMed]
  21. G. Yao and L. Wang, "Propagation of polarized light in turbid media: simulated animation sequences," Opt. Express 7, 198-203 (2000). [CrossRef] [PubMed]
  22. Y. Deng, S. Zeng, Q. Lu, D. zhu, and Q. Luo, "Characterization of backscattering Mueller matrix patterns of highly scattering media with triple scattering assumption," Opt. Express 15, 9672-9680 (2007). [CrossRef] [PubMed]
  23. C. Schwartz and A. Dogariu, "Backscattered polarization patterns determined by conservation of angular momentum," J. Opt. Soc. Am. A 25, 431-436 (2008). [CrossRef]
  24. X. D. Wang, G. Yao, and L. V. Wang, "Monte Carlo model and single-scattering approximation of the propagation of polarized light in turbid media containing glucose," Appl. Opt. 41, 792(2002). [CrossRef] [PubMed]
  25. M. G. Moharam and T. K. Gaylord, "Three Dimensional vector coupled-wave analysis of planer-grating diffraction," J. Opt. Soc. Am. 73, 1105-1112 (1983). [CrossRef]
  26. R. A. Thornhill, N. Thomas, and N. Berovic, "Optical diffraction by well ordered muscle fibers," Eur. Biophys. 20, 87-99 (1991).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited