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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 17 — Aug. 18, 2008
  • pp: 12423–12434

Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method

Haijing Niu, Ping Guo, Lijun Ji, Qing Zhao, and Tianzi Jiang  »View Author Affiliations


Optics Express, Vol. 16, Issue 17, pp. 12423-12434 (2008)
http://dx.doi.org/10.1364/OE.16.012423


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Abstract

Diffuse optical tomography (DOT) reconstructs the images of internal optical parameter distribution using noninvasive boundary measurements. The image reconstruction procedure is known to be an ill-posed problem. In order to solve such a problem, a regularization technique is needed to constrain the solution space. In this study, a projection-error-based adaptive regularization (PAR) technique is proposed to improve the reconstructed image quality. Simulations are performed using a diffusion approximation model and the simulated results demonstrate that the PAR technique can improve reconstruction precision of object more effectively. The method is demonstrated to have low sensitivity to noise at various noise levels. Moreover, with the PAR method, the detectability of an object located both at the center and near the peripheral regions has been increased largely.

© 2008 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 17, 2008
Revised Manuscript: June 16, 2008
Manuscript Accepted: July 15, 2008
Published: August 4, 2008

Virtual Issues
Vol. 3, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Haijing Niu, Ping Guo, Lijun Ji, Qing Zhao, and Tianzi Jiang, "Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method," Opt. Express 16, 12423-12434 (2008)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-17-12423


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