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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 19 — Sep. 15, 2008
  • pp: 15206–15211

Water-assisted femtosecond laser machining of electrospray nozzles on glass microfluidic devices

Ran An, Michelle D. Hoffman, Margaret A. Donoghue, Alan J. Hunt, and Stephen C. Jacobson  »View Author Affiliations

Optics Express, Vol. 16, Issue 19, pp. 15206-15211 (2008)

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Using water-assisted femtosecond laser machining, we fabricated electrospray nozzles on glass coverslips and on assembled microfluidic devices. Machining the nozzles after device assembly facilitated alignment of the nozzles over the microchannels. The basic nozzle design is a through-hole in the coverslip to pass liquids and a trough machined around the through-hole to confine the electrospray and prevent liquid from wicking across the glass surface. Electrospray from the nozzles was stable with and without pressure-driven flow applied and was evaluated using mass spectra of the peptide bradykinin.

© 2008 Optical Society of America

OCIS Codes
(190.7110) Nonlinear optics : Ultrafast nonlinear optics
(230.4000) Optical devices : Microstructure fabrication
(350.3390) Other areas of optics : Laser materials processing

ToC Category:
Laser Micromachining

Original Manuscript: August 19, 2008
Revised Manuscript: September 5, 2008
Manuscript Accepted: September 5, 2008
Published: September 11, 2008

Virtual Issues
Vol. 3, Iss. 11 Virtual Journal for Biomedical Optics

Ran An, Michelle D. Hoffman, Margaret A. Donoghue, Alan J. Hunt, and Stephen C. Jacobson, "Water-assisted femtosecond laser machining of electrospray nozzles on glass microfluidic devices," Opt. Express 16, 15206-15211 (2008)

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