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Optics Express

Optics Express

  • Editor: Martijn de Sterke
  • Vol. 16, Iss. 20 — Sep. 29, 2008
  • pp: 15949–15957

Specific detection of proteins using photonic crystal waveguides

S. C. Buswell, V. A. Wright, J. M. Buriak, V. Van, and S. Evoy  »View Author Affiliations


Optics Express, Vol. 16, Issue 20, pp. 15949-15957 (2008)
http://dx.doi.org/10.1364/OE.16.015949


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Abstract

Specific detection of proteins is demonstrated using planar photonic crystal waveguides. Using immobilized biotin as probe, streptavidin was captured, causing the waveguide mode cut-off to red-shift. The device was shown to detect a 2.5 nm streptavidin film with a 0.86 nm cut-off red-shift. An improved photonic crystal waveguide sensor design is also described and shown to have a 40% improved bulk refractive index response.

© 2008 Optical Society of America

OCIS Codes
(130.0130) Integrated optics : Integrated optics
(130.6010) Integrated optics : Sensors
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(130.5296) Integrated optics : Photonic crystal waveguides
(230.5298) Optical devices : Photonic crystals

ToC Category:
Photonic Crystals

History
Original Manuscript: June 30, 2008
Revised Manuscript: September 12, 2008
Manuscript Accepted: September 12, 2008
Published: September 23, 2008

Virtual Issues
Vol. 3, Iss. 11 Virtual Journal for Biomedical Optics

Citation
S. C. Buswell, V. A. Wright, J. M. Buriak, V. Van, and S. Evoy, "Specific detection of proteins using photonic crystal waveguides," Opt. Express 16, 15949-15957 (2008)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-20-15949


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