OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 22 — Oct. 27, 2008
  • pp: 17358–17365

Exploring the limits of single emitter detection in fluorescence and extinction

G. Wrigge, J. Hwang, I. Gerhardt, G. Zumofen, and V. Sandoghdar  »View Author Affiliations


Optics Express, Vol. 16, Issue 22, pp. 17358-17365 (2008)
http://dx.doi.org/10.1364/OE.16.017358


View Full Text Article

Enhanced HTML    Acrobat PDF (133 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We present an experimental comparison and a theoretical analysis of the signal-to-noise ratios in fluorescence and extinction spectroscopy of a single emitter. We show that because of its homodyne nature the extinction measurements can be advantageous if the emitter is weakly excited. Furthermore, we discuss the potential of this method for the detection and spectroscopy of weakly emitting systems such as rare earth ions.

© 2008 Optical Society of America

OCIS Codes
(270.1670) Quantum optics : Coherent optical effects
(300.1030) Spectroscopy : Absorption
(300.6390) Spectroscopy : Spectroscopy, molecular
(270.5585) Quantum optics : Quantum information and processing

ToC Category:
Spectroscopy

History
Original Manuscript: July 11, 2008
Revised Manuscript: September 18, 2008
Manuscript Accepted: September 27, 2008
Published: October 14, 2008

Citation
G. Wrigge, J. Hwang, I. Gehardt, G. Zumofen, and V. Sandoghdar, "Exploring the limits of single emitter detection in fluorescence and extinction," Opt. Express 16, 17358-17365 (2008)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-22-17358


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. F. Kulzer and M. Orrit, Single-Molecule Optics, Annu. Rev. Phys. Chem. 55, 585-611 (2004). [CrossRef] [PubMed]
  2. W. E. Moerner and L. Kador, "Optical Detection and Spectroscopy of Single Molecules in a Solid," Phys. Rev. Lett. 62, 2535-2538 (1989). [CrossRef] [PubMed]
  3. M. Orrit and J. Bernard, "Single Pentacene Molecules Detected by Fluorescence Excitation in a p-Terphenyl Crystal," Phys. Rev. Lett. 65, 2716-2719 (1990). [CrossRef] [PubMed]
  4. E. Shera, N. Seitzinger, L. Davis, R. Keller, and S. Soper, "Detection of single fluorescent molecules," Chem. Phys. Lett. 174, 553-557 (1990). [CrossRef]
  5. E. Betzig and R. J. Chichester, "Single Molecules Observed by Near-Field Scanning Optical Microscopy," Science 262, 1422-1425 (1993). [CrossRef] [PubMed]
  6. S. Nie, D. T. Chiu, and R. N. Zare, "Probing Individual Molecules with Confocal Fluorescence Microscopy," Science 266, 1018-1021 (1994). [CrossRef] [PubMed]
  7. T. Basche, W. E. Moerner, M. Orrit, and U. Wild, Single Molecule Spectroscopy (John Wiley and Sons, 1999).
  8. T. Plakhotnik and V. Palm, "Interferometric signatures of single molecules," Phys. Rev. Lett. 87, 183602 (2001). [CrossRef]
  9. J. R. Guest, T. H. Stievater, X. Li, J. Cheng, D. G. Steel, D. Gammon, D. S. Katzer, D. Park, C. Ell, A. Thranhardt, G. Khitrova, and H. M. Gibbs, "Measurement of optical absorption by a single quantum dot exciton," Phys. Rev. B. 65, 241310(R) (2002). [CrossRef]
  10. B. Alen, F. Bickel, K. Karrai, R. J. Warburton, and P. M. Petroff, "Stark-shift modulation absorption spectroscopy of single quantum dots," Appl. Phys. Lett. 83, 2235-2237 (2003). [CrossRef]
  11. I. Gerhardt, G. Wrigge, P. Bushev, G. Zumofen, M. Agio, R. Pfab, and V. Sandoghdar, "Strong extinction of a laser beam by a single molecule," Phys. Rev. Lett. 98, 033601 (2007). [CrossRef] [PubMed]
  12. I. Gerhardt, G. Wrigge, M. Agio, P. Bushev, G. Zumofen, and V. Sandoghdar, "Scanning Near-Field Optical Coherent Spectroscopy of Single Molecules at 1.4 Kelvin," Opt. Lett. 32, 1420-1422 (2007). [CrossRef] [PubMed]
  13. G. Wrigge, I. Gerhardt, J. Hwang, G. Zumofen, and V. Sandoghdar, "Efficient coupling of photons to a single molecule and the observation of its resonance fluorescence," Nature Phys. 4, 60-66 (2008). [CrossRef]
  14. C. Cohen-Tannoudji, J. Dupont-Roc, and G. Grynberg, Atom-Photon Interactions (John Wiley & Sons, Inc., 1992).
  15. D. Jackson, Classical Electrodynamics (Wiley and Sons, 1999).
  16. H. A. Haus, Electromagnetic Noise and Quantum Optical Measurements (Springer-Verlag, Heidelberg, 2000).
  17. H. P. Yuen and V. W. S. Chan, "Noise in homodyne and heterodyne detection," Opt. Lett. 8, 177 (1983). [CrossRef] [PubMed]
  18. G. Zumofen, N. M. Mojarad, V. Sandoghdar, and M. Agio, "Perfect Reflection of Light by an Oscillating Dipole," Phys. Rev. Lett. (to appear), http://arxiv.org/abs/0805.3231v2 (2008). [CrossRef] [PubMed]
  19. W. E. Moerner, "Examining Nanoenvironments in Solids on the Scale of a Single, Isolated Impurity Molecule," Science 265, 46-53 (1994). [CrossRef] [PubMed]
  20. T. Plakhotnik, "Absorption and coherent emission of single molecules," J. Lumin. 98, 57-62 (2002). [CrossRef]
  21. A. N. Vamivakas, M. Atature, J. Dreiser, S. T. Yilmaz, A. Badolato, A. K. Swan, B. B. Goldberg, A. Imamoglu, and M. S. Unlu, "Strong extinction of a far-field laser beam by a single quantum dot," Nano Lett. 7, 2892-2896 (2007). [CrossRef] [PubMed]
  22. P. Kukura, M. Celebrano, A. Renn, and V. Sandoghdar, "Seeing a single quantum emitter in its bright and dark states," Nano Lett. (DOI: 10.1021/nl801735y), http://arxiv.org/abs/0802.1206 (2008). [PubMed]
  23. A. A. Mikhailovsky, M. A. Petruska, M. I. Stockman, and V. I. Klimov, "Broadband near-field interference spectroscopy of metal nanoparticles using a femtosecond white-light continuum," Opt. Lett. 28, 1686-1688 (2003). [CrossRef] [PubMed]
  24. K. Lindfors, T. Kalkbrenner, P. Stoller, and V. Sandoghdar, "Detection and spectroscopy of gold nanoparticle using supercontinuum white light confocal microscopy," Phys. Rev. Lett. 93, 037401 (2004). [CrossRef] [PubMed]
  25. A. Arbouet, D. Christofilos, N. D. Fatti, F. Vall�??ee, J. R. Huntzinger, L. Arnaud, P. Billaud, and M. Broyer, "Direct measurement of the single-metal-cluster optical absorption," Phys. Rev. Lett. 93, 127401 (2004). [CrossRef] [PubMed]
  26. V. Jacobsen, P. Stoller, C. Brunner, V. Vogel, and V. Sandoghdar, "Interferometric optical detection and tracking of very small gold nanoparticles at a water-glass interface," Opt. Express 14, 405-414 (2006). [CrossRef] [PubMed]
  27. F. V. Ignatovich and L. Novotny, "Real-Time and Background-Free Detection of Nanoscale Particles," Phys. Rev. Lett. 96, 013901 (2006). [CrossRef] [PubMed]
  28. H. Ewers, V. Jacobsen, E. Klotzsch, A. E. Smith, A. Helenius, and V. Sandoghdar, "Label-free Optical Detection and Tracking of Single Virions Bound to their Receptor in Supported Membrane Bilayers," Nano Lett. 7, 2263-2266 (2007). [CrossRef] [PubMed]
  29. S. Schultz, D. R. Smith, J. J. Mock, and D. A. Schultz, "Single-target molecule detection with nonbleaching multicolor optical immunolabels," PNAS 97, 996-1001 (2000). [CrossRef] [PubMed]
  30. C. Sonnichsen, S. Geier, N. E. Hecker, G. von Plessen, J. Feldmann, H. Ditlbacher, b. Lamprecht, J. R. Krenn, F. R. Aussenegg, V. Z.-H. Chan, J. P. Spatz, and M. M¨oller, "Spectroscopy of single metallic nanoparticles using total internal reflection microscopy," Appl. Phys. Lett. 77, 2949-2951 (2000). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1. Fig. 2. Fig. 3.
 
Fig. 4.
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited