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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 4 — Feb. 18, 2008
  • pp: 2405–2414

High sensitive measurement of the human axial eye length in vivo with Fourier domain low coherence interferometry

Branislav Grajciar, Michael Pircher, Christoph K. Hitzenberger, Oliver Findl, and Adolf F. Fercher  »View Author Affiliations

Optics Express, Vol. 16, Issue 4, pp. 2405-2414 (2008)

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In this paper we present a system for intraocular distance measurement of the human eye in vivo with high sensitivity. The instrument is based on Fourier domain low coherence interferometry (FD-LCI). Stateof-the-art FD-LCI systems are limited to a depth range of only a few mm, because the depth range is determined by the spectral resolution of the spectrometer. To measure larger distances (e.g. human eye length) we implemented two separate reference arms with different arm lengths into the interferometer. Each reference arm length corresponds to a different depth position within the sample (e.g. cornea and retina). Therefore two different depth sections, each with a depth range of a few mm can be imaged simultaneously. With the new system axial distances could be measured with a precision of 8µm. We demonstrate the performance of the instrument by measuring the axial eye length of 9 patients with cataract and compare our results with those obtained using the IOL Master (Carl Zeiss Meditec Inc.).

© 2008 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: December 7, 2007
Revised Manuscript: January 16, 2008
Manuscript Accepted: January 28, 2008
Published: February 5, 2008

Virtual Issues
Vol. 3, Iss. 3 Virtual Journal for Biomedical Optics

Branislav Grajciar, Michael Pircher, Christoph K. Hitzenberger, Oliver Findl, and Adolf F. Fercher, "High sensitive measurement of the human axial eye length in vivo with Fourier domain low coherence interferometry," Opt. Express 16, 2405-2414 (2008)

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