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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 9 — Apr. 28, 2008
  • pp: 6274–6284

Early dental caries detection using a fibre-optic coupled polarization-resolved Raman spectroscopic system

Alex C.-T. Ko, Mark Hewko, Michael G. Sowa, Cecilia C.S. Dong, Blaine Cleghorn, and Lin-P’ing Choo-Smith  »View Author Affiliations

Optics Express, Vol. 16, Issue 9, pp. 6274-6284 (2008)

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A new fibre-optic coupled polarization-resolved Raman spectroscopic system was developed for simultaneous collection of orthogonally polarized Raman spectra in a single measurement. An application of detecting incipient dental caries based on changes observed in Raman polarization anisotropy was also demonstrated using the developed fibre-optic Raman spectroscopic system. The predicted reduction of polarization anisotropy in the Raman spectra of caries lesions was observed and the results were consistent with those reported previously with Raman microspectroscopy. The capability of simultaneous collection of parallel-and cross-polarized Raman spectra of tooth enamel in a single measurement and the improved laser excitation delivery through fibre-optics demonstrated in this new design illustrates its future clinical potential.

© 2008 Optical Society of America

OCIS Codes
(170.1850) Medical optics and biotechnology : Dentistry
(170.5660) Medical optics and biotechnology : Raman spectroscopy

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: March 7, 2008
Revised Manuscript: April 9, 2008
Manuscript Accepted: April 15, 2008
Published: April 21, 2008

Virtual Issues
Vol. 3, Iss. 5 Virtual Journal for Biomedical Optics

Alex C. Ko, Mark Hewko, Michael G. Sowa, Cecilia C. Dong, Blaine Cleghorn, and Lin-P'ing Choo-Smith, "Early dental caries detection using a fibre-optic coupled polarization-resolved Raman spectroscopic system," Opt. Express 16, 6274-6284 (2008)

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  1. J. Bader, "Diagnosis and management of dental caries," Number 36. AHRQ Publication No.01-E055, February 2001. Rockville, MD: Agency for Healthcare Research and Quality.
  2. A. I. Ismail, "Visual and Visuo-tactile detection of dental caries," J. Dent Res. 83, C56-C66 (2004). [CrossRef] [PubMed]
  3. A. Schneiderman, M. Elbaum, T. Schultz, S. Keem, M. Greenebaum, and J. Driller, "Assessment of Dental caries with Digital Imaging Fiber-Optic Transillumination (DIFOTI): in vitro study," Caries Res. 31, 103-110 (1997). [CrossRef] [PubMed]
  4. E. de Josselin de Jong, F. Sundström, H. Westerling, S. Tranaeus, J. J. ten Bosch and B. Angmar-Månsson; "A new method for in vivo quantification of changes in initial enamel caries with laser fluorescence," Caries Res. 29, 2-7 (1995). [CrossRef] [PubMed]
  5. G. K. Stookey, R. D. Jackson, A. G. Zandona, and M. Abaloui, "Dental caries diagnosis," Dent. Clin. North Am. 43, 665-677 (1999). [PubMed]
  6. J. M. Girkin, A. F. Hall, and S. L. Creanor, "Two-photon imaging of intact dental tissue," Dental Caries 2, 317-325 (2000).
  7. K. Kaneko, K. Matsuyama, and S. Nakashima, "Quantification of early carious enamel lesions by using an infrared camera in vitro," in Proceedings of the 4th annual Indiana conference, G. K. Stookey, ed., (Indiana University School of Dentistry, Indianapolis, Indiana 1999) pp. 83-100.
  8. D. A. Crawley, L. Longbottom, B. C. Cole, C. M. Ciesla, D. Arnone, V. P. Wallace, and M. Pepper, "Tetrahertz pulse imaging: a pilot study of potential applications in dentistry," Caries Res. 37, 352-359 (2003). [CrossRef] [PubMed]
  9. B. T. Amaechi, S. M. Higham, A. G. Podoleanu, J. A. Rogers, and D. A. Jackson, "Use of optical coherence tomography for assessment of dental caries: quantitative procedure," J. Oral Rehabil. 28, 1092-1093 (2001). [CrossRef]
  10. W. Hill and V. Petrou, "Caries detection by diode laser Raman spectroscopy," Appl. Spectrosc. 54, 795-799 (2000). [CrossRef]
  11. A. C.-T. Ko, L. P. Choo-Smith, M. Hewko, L. Leonardi, M. G. Sowa, C. C. S. Dong, P. Williams, and B. Cleghorn, "Ex vivo detection and characterization of early dental caries by optical coherence tomography and Raman spectroscopy," J. Biomed. Opt. 10, 031118 (2005). [CrossRef] [PubMed]
  12. R. S. Jones, G. D. Huynh, G. C. Jones, and D. Fried, "Near-infrared transillumination at 1310-nm for the imaging of early dental decay," Opt. Express 11, 2259-2265 (2003). [CrossRef] [PubMed]
  13. C. M. Bühler, P. Ngaotheppitak, and D. Fried, "Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm," Opt. Express 13, 573-582 (2005). [CrossRef] [PubMed]
  14. G. K. Stookey, "Optical Methods??Quantitative Light Fluorescence," J. Dent. Res. 83, C84-C88 (2004) [CrossRef] [PubMed]
  15. A. C. -T. Ko, L. -P. Choo-Smith, M. Hewko, M. G. Sowa, C. C. S. Dong, and B. Cleghorn, "Detection of early dental caries using polarized Raman spectroscopy," Opt. Express 14, 203-215 (2006). [CrossRef] [PubMed]
  16. G. A. Thomson, K. J. Baldwin, and D. N. Batchelder, "Raman spectroscopy with simultaneous measurement of two orthogonally polarized Raman spectra," J. Raman Spectrosc. 34, 345-349 (2003). [CrossRef]
  17. C. Bremard, P. Dhamelincourt, J. Laureynes, and G. Turrell, "The effect of high-numerical-aperture objectives on polarization measurements in micro-Raman spectrometry," Appl. Spectrosc. 39, 1036-1039 (1985). [CrossRef]

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