OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 10 — May. 11, 2009
  • pp: 8185–8192

Optics InfoBase > Optics Express > Volume 17 > Issue 10 > Page 8185

Determination of post-mortem interval using in situ tissue optical fluorescence

Éverton Sérgio Estracanholli, Cristina Kurachi, José Renato Vicente, Priscila Fernanda Campos de Menezes, Orlando Castro e Silva Júnior, and Vanderlei Salvador Bagnato  »View Author Affiliations


Optics Express, Vol. 17, Issue 10, pp. 8185-8192 (2009)
http://dx.doi.org/10.1364/OE.17.008185


View Full Text Article

Enhanced HTML    Acrobat PDF (169 KB)


Advanced Search

Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

In this study we have used fluorescence spectroscopy to determine the post-mortem interval. Conventional methods in forensic medicine involve tissue or body fluids sampling and laboratory tests, which are often time demanding and may depend on expensive analysis. The presented method consists in using time-dependent variations on the fluorescence spectrum and its correlation with the time elapsed after regular metabolic activity cessation. This new approach addresses unmet needs for post-mortem interval determination in forensic medicine, by providing rapid and in situ measurements that shows improved time resolution relative to existing methods.

© 2009 OSA

OCIS Codes
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: December 9, 2008
Revised Manuscript: January 31, 2009
Manuscript Accepted: April 25, 2009
Published: April 30, 2009

Virtual Issues
Vol. 4, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Éverton Sérgio Estracanholli, Cristina Kurachi, José Renato Vicente, Priscila Fernanda Campos de Menezes, Orlando Castro e Silva Júnior, and Vanderlei Salvador Bagnato, "Determination of post-mortem interval using in situ tissue optical fluorescence," Opt. Express 17, 8185-8192 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-10-8185


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. P. Vanezis and O. Trujillo, “Evaluation of hypostasis using a colorimeter measuring system and its application to assessment of the post-mortem interval (time of death),” Forensic Sci. Int. 78(1), 19–28 (1996). [CrossRef] [PubMed]
  2. E. Scheurer, M. Ith, D. Dietrich, R. Kreis, J. Hüsler, R. Dirnhofer, and C. Boesch, “Statistical evaluation of time-dependent metabolite concentrations: estimation of post-mortem intervals based on in situ 1H-MRS of the brain,” NMR Biomed. 18(3), 163–172 (2005). [CrossRef]
  3. A. J. Sabucedo and K. G. Furton, “Estimation of postmortem interval using the protein marker cardiac Troponin I,” Forensic Sci. Int. 134(1), 11–16 (2003). [CrossRef] [PubMed]
  4. L. A. Johnson and J. A. J. Ferris, “Analysis of postmortem DNA degradation by single-cell gel electrophoresis,” Forensic Sci. Int. 126(1), 43–47 (2002). [CrossRef] [PubMed]
  5. A. D. Stan, S. Ghose, X. M. Gao, R. C. Roberts, K. Lewis-Amezcua, K. J. Hatanpaa, and C. A. Tamminga, “Human postmortem tissue: what quality markers matter?” Brain Res. 1123(1), 1–11 (2006). [CrossRef] [PubMed]
  6. B. Zhou, L. Zhang, G. Zhang, X. Zhang, and X. Jiang, “The determination of potassium concentration in vitreous humor by low pressure ion chromatography and its application in the estimation of postmortem interval,” J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 852(1-2), 278–281 (2007). [CrossRef] [PubMed]
  7. B. Madea and A. Rödig, “Time of death dependent criteria in vitreous humor: accuracy of estimating the time since death,” Forensic Sci. Int. 164(2-3), 87–92 (2006). [CrossRef] [PubMed]
  8. D. Querido, “A preliminary investigation into postmortem changes in skinfold impedance during the early postmortem period in rats,” Forensic Sci. Int. 96(2-3), 107–114 (1998). [CrossRef] [PubMed]
  9. M. J. Prieto-Castelló, J. P. Hernández del Rincón, C. Pérez-Sirvent, P. Alvarez-Jiménez, M. D. Pérez-Cárceles, E. Osuna, and A. Luna, “Application of biochemical and X-ray diffraction analyses to establish the postmortem interval,” Forensic Sci. Int. 172(2-3), 112–118 (2007). [CrossRef] [PubMed]
  10. T. E. Huntington, L. G. Higley, and F. P. Baxendale, “Maggot development during morgue storage and its effect on estimating the post-mortem interval,” J. Forensic Sci. 52(2), 453–458 (2007). [CrossRef] [PubMed]
  11. J. Amendt, C. P. Campobasso, E. Gaudry, C. Reiter, H. N. LeBlanc, M. J. Hall, and European Association for Forensic Entomology, “Best practice in forensic entomology--standards and guidelines,” Int. J. Legal Med. 121(2), 90–104 (2007). [CrossRef]
  12. G. A. Wagnières, W. M. Star, and B. C. Wilson, “In vivo fluorescence spectroscopy and imaging for oncological applications,” Photochem. Photobiol. 68(5), 603–632 (1998). [PubMed]
  13. V. B. Loschenov, V. I. Konov, and A. M. Prokhorov, “Photodynamic therapy and fluorescence diagnostics,” Laser Phys. 10, 1188–1207 (2000).
  14. G. K. Stookey, “The evolution of caries detection,” Dimensions of Dental Hygiene 10, 12–14 (2003).
  15. C. Meller, C. Heyduck, S. Tranaeus, and C. Splieth, “A new in vivo method for measuring caries activity using quantitative light-induced fluorescence,” Caries Res. 40(2), 90–96 (2006). [CrossRef] [PubMed]
  16. A. G. Doukas, M. Bamberg, R. Gillies, R. Evans, and N. Kollias, “Spectroscopic determination of skin viability. A predictor of postmortem interval,” J. Forensic Sci. 45(1), 36–41 (2000). [PubMed]
  17. A. M. C. Davies and T. Fearn, “Back to basics: the principles of principal component analysis,” Spectroscopy Europe 16(6), 20–23 (2005).
  18. L. F. Costa, Shape analysis and classification: theory and practice. (Crc Press, 2001).

Cited By

 Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited