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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 14 — Jul. 6, 2009
  • pp: 11665–11672

Reconstruction of in-vivo optical properties for human prostate using interstitial diffuse optical tomography

Ken Kang-Hsin Wang and Timothy C. Zhu  »View Author Affiliations

Optics Express, Vol. 17, Issue 14, pp. 11665-11672 (2009)

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A CW interstitial diffuse optical tomography has been developed to characterize the in-vivo optical properties of prostate gland during photodynamic therapy. The spatial distributions of light fluence rate can be described by the diffusion equation. Optical properties of the prostate are reconstructed by solving the inverse problem with an adjoint method. The 3D reconstructed in-vivo optical properties for a human prostate is illustrated and compared with the results generated by a well-established point-by-point method. Moreover, the calculated fluence rate using the reconstructed optical properties matches the measured data.

© 2009 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5180) Medical optics and biotechnology : Photodynamic therapy
(170.6960) Medical optics and biotechnology : Tomography
(170.7230) Medical optics and biotechnology : Urology

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: May 4, 2009
Revised Manuscript: June 9, 2009
Manuscript Accepted: June 22, 2009
Published: June 26, 2009

Virtual Issues
Vol. 4, Iss. 9 Virtual Journal for Biomedical Optics

Ken Kang-Hsin Wang and Timothy C. Zhu, "Reconstruction of in-vivo optical properties for human prostate using interstitial diffuse optical tomography," Opt. Express 17, 11665-11672 (2009)

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