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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 14 — Jul. 6, 2009
  • pp: 12121–12131

Development of a non-uniform discrete Fourier transform based high speed spectral domain optical coherence tomography system

Kai Wang, Zhihua Ding, Tong Wu, Chuan Wang, Jie Meng, Minghui Chen, and Lei Xu  »View Author Affiliations


Optics Express, Vol. 17, Issue 14, pp. 12121-12131 (2009)
http://dx.doi.org/10.1364/OE.17.012121


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Abstract

We develop a high speed spectral domain optical coherence tomography (SD-OCT) system based on a custom-built spectrometer and non-uniform discrete Fourier transform (NDFT) to realize minimized depth dependent sensitivity fall-off. After precise spectral calibration of the spectrometer, NDFT of the acquired spectral data is adopted for image reconstruction. The spectrometer is able to measure a wavelength range of about 138nm with a spectral resolution of 0.0674nm at central wavelength of 835nm, corresponding to an axial imaging range of 2.56mm in air. Zemax simulations and sensitivity fall-off measurements under two alignment states of the spectrometer are given. Both theoretical simulations and experiments are done to study the depth dependent sensitivity of the developed system based on NDFT in contrast to those based on conventional discrete Fourier transform (DFT) with and without interpolation. In vivo imaging on human finger from volunteer is conducted at A-scan rate of 29 kHz and reconstruction is done based on different methods. The comparing results confirm that reconstruction method based on NDFT indeed improves sensitivity especially at large depth while maintaining the coherence-function-limited depth resolution.

© 2009 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(120.6200) Instrumentation, measurement, and metrology : Spectrometers and spectroscopic instrumentation
(070.2025) Fourier optics and signal processing : Discrete optical signal processing

ToC Category:
Imaging Systems

History
Original Manuscript: April 23, 2009
Revised Manuscript: May 27, 2009
Manuscript Accepted: June 22, 2009
Published: July 2, 2009

Virtual Issues
Vol. 4, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Kai Wang, Zhihua Ding, Tong Wu, Chuan Wang, Jie Meng, Minghui Chen, and Lei Xu, "Development of a non-uniform discrete Fourier transform based high speed spectral domain optical coherence tomography system," Opt. Express 17, 12121-12131 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-14-12121


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