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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 18 — Aug. 31, 2009
  • pp: 16111–16118

Single fluorescent gold nanoclusters

C. T. Yuan, W. C. Chou, J. Tang, C. A. Lin, W. H. Chang, J. L. Shen, and D. S. Chuu  »View Author Affiliations

Optics Express, Vol. 17, Issue 18, pp. 16111-16118 (2009)

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Both ensemble and single-molecule measurements were performed to explore the fluorescence properties of Au nanoclusters (NCs). Photoinduced fluorescence enhancement was observed for ensemble NCs in solution, but photobleaching was found at ambient environments. At the single-molecule level, fluorescence blinking and single-step photobleaching were observed. Furthermore, their time-resolved fluorescence shows a single exponential decay with a lifetime of ~7 ns and is insensitive to changes in fluorescence intensity. The lifetime distribution is more homogeneous within ensemble Au NCs as compared to CdSe QDs. Therefore, Au NCs have potential applications as nontoxic fluorescent labels for lifetime-based imaging microscopy. However, their low quantum yields and poor photostability are disadvantageous factors, which require further improvement.

© 2009 Optical Society of America

OCIS Codes
(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 29, 2009
Revised Manuscript: June 11, 2009
Manuscript Accepted: June 12, 2009
Published: August 26, 2009

Virtual Issues
Vol. 4, Iss. 10 Virtual Journal for Biomedical Optics

C. T. Yuan, W. C. Chou, J. Tang, C. A. Lin, W. H. Chang, J. L. Shen, and D. S. Chuu, "Single fluorescent gold nanoclusters," Opt. Express 17, 16111-16118 (2009)

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