OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 2 — Jan. 19, 2009
  • pp: 1003–1015

Interferometric 3D tracking of several particles in a scanning laser focus

Michael Speidel, Lars Friedrich, and Alexander Rohrbach  »View Author Affiliations


Optics Express, Vol. 17, Issue 2, pp. 1003-1015 (2009)
http://dx.doi.org/10.1364/OE.17.001003


View Full Text Article

Enhanced HTML    Acrobat PDF (834 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

High-Speed tracking of several particles allows measuring dynamic long-range interactions relevant to biotechnology and colloidal physics. In this paper we extend the successful technique of 3D back-focal plane interferometry to oscillating laser beams and show that two or more particles can be trapped and tracked with a precision of a few nanometers in all three dimensions. The tracking rate of several kHz is only limited by the scan speed of the beam steering device. Several tests proof the linearity and orthogonality of our detection scheme, which is of interest to optical tweezing applications and various metrologies. As an example we show the position cross-correlations of three diffusing particles in a scanning line optical trap.

© 2009 Optical Society of America

OCIS Codes
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(140.7010) Lasers and laser optics : Laser trapping
(260.3160) Physical optics : Interference
(290.0290) Scattering : Scattering

ToC Category:
Optical Trapping and Manipulation

History
Original Manuscript: December 2, 2008
Revised Manuscript: January 12, 2009
Manuscript Accepted: January 12, 2009
Published: January 13, 2009

Virtual Issues
Vol. 4, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Michael Speidel, Lars Friedrich, and Alexander Rohrbach, "Interferometric 3D tracking of several particles in a scanning laser focus," Opt. Express 17, 1003-1015 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-2-1003


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. Weihs, T. G. Mason, and M. A. Teitell, "Bio-Microrheology: A Frontier in Microrheology," Biophys. J. 91, 4296-4305 (2006). [CrossRef] [PubMed]
  2. M. Brunner, J. Dobnikar, H. H. von Grunberg, and C. Bechinger, "Direct measurement of three-body interactions amongst charged colloids," Phys. Rev. Lett. 92, 078301 (2004). [CrossRef] [PubMed]
  3. J. C. Crocker, J. A. Matteo, A. D. Dinsmore, and A. G. Yodh, "Entropic attraction and repulsion in binary colloids probed with a line optical tweezer," Phys. Rev. Lett. 82, 4352-4355 (1999). [CrossRef]
  4. J.-C. Meiners and S. R. Quake, "Direct Measurement of Hydrodynamic Cross Correlations between Two Particles in an External Potential," Phys. Rev. Lett. 82, 2211 (1999). [CrossRef]
  5. S. Henderson, S. Mitchell, and P. Bartlett, "Direct measurements of colloidal friction coefficients," Phys.Rev. E 64, 061403 (2001). [CrossRef]
  6. M. Atakhorrami, K. M. Addas, and C. F. Schmidt, "Twin optical traps for two-particle cross-correlation measurements: Eliminating cross-talk," Rev. Sci. Instr. 79, 043103 (2008). [CrossRef]
  7. M. Polin, Y. Roichman, and D. G. Grier, "Autocalibrated colloidal interaction measurements with extended optical traps," Phys.Rev. E 77, 051401-051407 (2008). [CrossRef]
  8. G. Gibson, J. Leach, S. Keen, A. J. Wright, and M. J. Padgett, "Measuring the accuracy of particle position and force in optical tweezers using high-speed video microscopy," Opt. Express 16, 14561-14570 (2008). [CrossRef] [PubMed]
  9. M. Speidel, A. Jonas, and E. L. Florin, "Three-dimensional tracking of fluoroscent nanoparticles with subnanometer precision by use of off-focus imaging," Opt. Lett. 28, 69-71 (2003). [CrossRef] [PubMed]
  10. Z. Zhang and C.-H. Menq, "Three-dimensional particle tracking with subnanometer resolution using off-focus images," Appl. Opt. 47, 2361-2370 (2008). [CrossRef] [PubMed]
  11. S.-H. Lee, Y. Roichman, G.-R. Yi, S.-H. Kim, S.-M. Yang, A. van Blaaderen, P. van Oostrum, and D. G. Grier, "Characterizing and tracking single colloidal particles with video holographic microscopy," Opt. Express 15, 18275-18282 (2007). [CrossRef] [PubMed]
  12. L. P. Faucheux, G. Stolovitzky, and A. Libchaber, "Periodic Forcing of a Brownian Particle," Phys.Rev. E 51, 5239-5250 (1995). [CrossRef]
  13. R. Verma, J. C. Crocker, T. C. Lubensky, and A. G. Yodh, "Entropic colloidal interactions in concentrated DNA solutions," Phys. Rev. Lett. 81, 4004-4007 (1998). [CrossRef]
  14. J. Dobnikar, M. Brunner, H. H. von Grunberg, and C. Bechinger, "Three-body interactions in colloidal systems," Phys. Rev. E 69, 031402 (2004). [CrossRef]
  15. F. Gittes and C. F. Schmidt, "Interference model for back-focal-plane displacement detection in optical tweezers," Opt. Lett. 23, 7-9 (1998). [CrossRef]
  16. A. Rohrbach, C. Tischer, D. Neumayer, E. L. Florin, and E. H. K. Stelzer, "Trapping and tracking a local probe with a Photonic Force Microscope," Rev. Sci. Instrum. 75, 2197-2210 (2004). [CrossRef]
  17. A. Pralle, M. Prummer, E.-L. Florin, E. H. K. Stelzer, and J. K. H. Hörber, "Three-dimensional position tracking for optical tweezers by forward scattered light," Microscopy Research and Techniques 44, 378-386 (1999). [CrossRef]
  18. R. Nambiar and J. C. Meiners, "Fast position measurements with scanning line optical tweezers," Opt. Lett. 27, 836-838 (2002). [CrossRef]
  19. D. Neumayer, P. Kaiser, E. H. K. Stelzer, and A. Rohrbach, "Interferometric tracking of two particles with dynamic optical traps," Proc. SPIE 5859, 33-39 (2005).
  20. A. Rohrbach, H. Kress, and E. H. K. Stelzer, "Three-dimensional tracking of small spheres in focused laser beams: influence of the detection angular aperture," Opt. Lett. 28, 411 - 413 (2003). [CrossRef] [PubMed]
  21. J. K. Dreyer, K. Berg-Sorensen, and L. Oddershede, "Improved axial position detection in optical tweezers measurements," Appl. Opt. 43, 1991-1995 (2004). [CrossRef] [PubMed]
  22. A. Rohrbach and E. H. K. Stelzer, "Three-dimensional position detection of optically trapped dielectric particles," J. Appl. Phys. 91, 5474-5488 (2002). [CrossRef]
  23. J. Baumgartl, "Like-charge attraction in confinement: myth or truth?," Soft Matter 2, 631-635 (2006). [CrossRef]
  24. P. C. Seitz, E. H. K. Stelzer, and A. Rohrbach, "Interferometric tracking of optically trapped probes behind structured surfaces: a phase correction method," Appl. Opt. 45, 7903-7915 (2006). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited