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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 20 — Sep. 28, 2009
  • pp: 18229–18240

Dual wavefront sensing channel monocular adaptive optics system for accommodation studies

Karen M. Hampson, Sem Sem Chin, and Edward A. H. Mallen  »View Author Affiliations

Optics Express, Vol. 17, Issue 20, pp. 18229-18240 (2009)

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Manipulation of the eye’s aberrations using adaptive optics (AO) has shown that optical imperfections can affect the dynamic accommodation response. A limitation of current system designs used for such studies is an inability to make direct measurements of the eye’s aberrations during the experiment. We present an AO system which has a dual wavefront sensing channel. The corrective device is a 37-actuator piezoelectric deformable mirror. The measurements used to control the mirror, and direct measurements of the eye’s aberrations, are captured on a single Shack-Hartmann sensor. Other features of the system include stroke amplification of the deformable mirror and a rotating diffuser to reduce speckle. We demonstrate the utility of the system by investigating the impact of aberration dynamics on the control of steady-state accommodation on four subjects.

© 2009 Optical Society of America

OCIS Codes
(330.7322) Vision, color, and visual optics : Visual optics, accommodation
(220.1080) Optical design and fabrication : Active or adaptive optics

ToC Category:
Adaptive Optics

Original Manuscript: June 24, 2009
Revised Manuscript: August 17, 2009
Manuscript Accepted: September 17, 2009
Published: September 25, 2009

Virtual Issues
Vol. 4, Iss. 11 Virtual Journal for Biomedical Optics

Karen M. Hampson, Sem Sem Chin, and Edward A. Mallen, "Dual wavefront sensing channel monocular adaptive optics system for accommodation studies," Opt. Express 17, 18229-18240 (2009)

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  1. H. Hofer, P. Artal, B. Singer, J. L. Arag’on, and D. R. Williams, "Dynamics of the eye’s wave aberration," J. Opt. Soc. Am. A 18, 497-506 (2001). [CrossRef]
  2. J. W. Hardy, J. E. Lefebvre, and C. L. Koliopoulos, "Real-time atmospheric compensation," J. Opt. Soc. Am. A 67, 360-369 (2001).
  3. E. J. Fern’andez, I. Iglesias, and P. Artal, "Closed-loop adaptive optics in the human eye," Opt. Lett. 26, 746-748 (2001). [CrossRef]
  4. H. Hofer, L. Chen, G. Y. Yoon, B. Singer, Y. Yamauchi, and D. R. Williams, "Improvement in retinal image quality with dynamic correction of the eye’s aberrations," Opt. Express 8, 631-643 (2001). [CrossRef] [PubMed]
  5. K. M. Hampson, "Topical review: Adaptive optics and vision," J. Mod. Opt. 55, 3425-3467 (2008). [CrossRef]
  6. E. F. Fincham, "The accommodation reflex and its stimulus," Brit. J. Ophthal. 35, 381-393 (1951). [CrossRef] [PubMed]
  7. G. Walsh andW. N. Charman, "The effect of defocus on the contrast and phase of the retinal image of a sinusoidal grating," Ophthal. Physiol. Opt. 9, 398-404 (1989). [CrossRef]
  8. B. J. Wilson, K. E. Decker, and A. Roorda, "Monochromatic aberrations provide an odd-error cue to focus direction," J. Opt. Soc. Am. A 19, 833-839 (2002). [CrossRef]
  9. E. J. Fern’andez and P. Artal, "Study on the effects of monochromatic aberrations in the accommodation response by using adaptive optics," J. Opt. Soc. Am. A 22, 1732-1738 (2005). [CrossRef]
  10. L. Chen, P. B. Kruger, H. Hofer, B. Singer, and D. R. Williams, "Accommodation with higher-order monochromatic aberrations corrected with adaptive optics," J. Opt. Soc. Am. A 23, 1-8 (2006). [CrossRef]
  11. E. Gambra, L. Sawides, C. Dorronsoro, and S. Marcos, "Accommodative lag and fluctuations when optical aberrations are manipulated," J. Vis. 9, 1-15 (2009). [CrossRef] [PubMed]
  12. B. Theagarayan, H. Radhakrishnan, P. M. Allen, R. I. Calver, S. M. Rae, and D. J. O’Leary, "The effect of altering spherical aberration on the static accommodative response," Ophthal. Physiol. Opt. 29, 65-71 (2009). [CrossRef]
  13. W. N. Charman and G. Heron, "Fluctuations in accommodation: A review," Ophthal. Physiol. Opt. 8, 153-164 (1988). [CrossRef]
  14. B. Winn, "Accommodative microfluctuations: a mechanism for steady-state control of accommodation," in Accommodation and vergence mechanisms of the visual system, O. Franz’en, H. Richter, and L. Stark, eds. (Birkh¨auser Verlag Basel, Switzerland, 2000), 129-140.
  15. L. S. Gray, B. Winn, and B. Gilmartin, "Effect of target luminance on microfluctuations of accommodation," Ophthal. Physiol. Opt. 13, 258-265 (1993). [CrossRef]
  16. M. Day, D. Seidel, L. S. Gray, and N. C. Strang, "The effect of modulating ocular depth of focus upon accommodation microfluctuations in myopic and emmetropic subjects," Vision Res. 49, 211-218 (2009). [CrossRef]
  17. L. S. Gray, B. Winn, and B. Gilmartin, "Accommodation microfluctuations and pupil diameter," Vision Res. 33, 2083-2090 (1993). [CrossRef] [PubMed]
  18. L. R. Stark and D. A. Atchison, "Pupil size, mean accommodation response and the flutuations of accommodation," Opthal. Physiol. Opt. 17, 316-323 (1997). [CrossRef]
  19. K. Niwa and T. Tokoro, "Influence of spatial distribution with blur on fluctuations in accommodation," Optom. Vis. Sci. 75, 227-232 (1998). [CrossRef] [PubMed]
  20. K. M. Hampson, C. Paterson, C. Dainty, and E. A. H. Mallen, "Adaptive optics system for investigation of the effect of the aberration dynamics of the human eye on steady-state accommodation control," J. Opt. Soc. Am. A 23, 1082-1088 (2006). [CrossRef]
  21. K. M. Hampson, S. S. Chin, and E. A. H. Mallen, "Binocular Shack-Hartmann sensor for the human eye," J. Mod. Opt. 55, 703-716 (2008). [CrossRef]
  22. British Standards: Safety of Laser Products, 60825-1:1994.
  23. R. H. Webb, M. J. Albanese, Y. Zhou, T. Bifano, and S. A. Burns, "Stroke amplifier for deformable mirrors," Appl. Opt. 43, 5330-5333 (2004). [CrossRef] [PubMed]
  24. L. N. Thibos, R. A. Applegate, J. T. Schwiegerling, and R. Webb, "Standards for reporting the optical aberrations of eyes," J. Refract. Surg. 18, 652-660 (2002).
  25. L. N. Thibos, W. Wheeler, and D. Horner, "Power vectors: an application of Fourier analysis," Optom. Vis. Sci. 74, 367-375 (1997). [CrossRef] [PubMed]
  26. J. M. Bland and D. G. Altman, "Statistical methods for assessing agreement between two methods of clinical measurement," Lancet 1, 307-310 (1986). [CrossRef] [PubMed]
  27. K. M. Hampson, E. A. H. Mallen, and C. Dainty "Coherence function analysis of the higher-order aberrations of the human eye," Opt. Lett. 31, 184-186 (2006). [CrossRef] [PubMed]
  28. L. Diaz-Santana, V. Gu’eriaux, G. Arden, and S. Gruppetta, "New methodology to measure the dynamics of ocular wave front aberrations during small amplitude changes of accommodation," Opt. Express 15, 5649-5663 (2007). [CrossRef] [PubMed]
  29. D. R. Iskander, M. J. Collins, M. R. Morelande, and M. Zhu, "Analyzing the dynamic wavefront aberrations in the human eye," IEEE Trans. Biomed. Eng. 51, 1969-1980 (2004). [CrossRef] [PubMed]
  30. M. G. Doane, "Interactions of eyelid and tears in corneal wetting and the dynamics of the normal human eye blink," A. J. Ophthal. 89, 507-516 (1988).
  31. L. N. Thibos, X. Hong, A. Bradley, and R. A. Applegate, "Accuracy and precision of objective refraction from wavefront aberrations," J. Vis. 4, 329-351 (2004). [CrossRef] [PubMed]
  32. J. S. Bendat and A. G. Piersol, Random data: analysis and measurement procedures, (Jon Wiley & Sons, Inc., New York, 2000).
  33. P. Denieul, "Effects of stimulus vergence on mean accommodation response, micofluctuations of accommodation and the optical quality of the human eye," Vision Res. 22, 561-569 (1882). [CrossRef]
  34. S. S. Chin, K. M. Hampson, and E. A. H. Mallen, "Role of ocular aberrations in dynamic accommodation control," Clin. Exp. Optom. 92, 227-237 (2009). [CrossRef] [PubMed]
  35. Q. Mu, Z. Cao, D. Li, L. Hu, and L. Xuan, "Open-loop corection of horizontal turbulence: system design and result," Appl. Opt. 47, 4297-4301 (2008). [CrossRef] [PubMed]
  36. L. R. Stark, N. C. Strang, and D. A. Atchison, "Dynamic accommodation response in the presence of astigmatism," J. Opt. Soc. Am. A 20, 2228-2236, (2003). [CrossRef]
  37. M. J. Collins and B. A. Davis, "Microfluctuations of accommodation and spherical aberration," Clin. Exp. Optom. 80, 234 (1997).

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