OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 23 — Nov. 9, 2009
  • pp: 21271–21279

Spectral analysis of induced color change on periodically nanopatterned silk films

Jason J. Amsden, Hannah Perry, Svetlana V. Boriskina, Ashwin Gopinath, David L. Kaplan, Luca Dal Negro, and Fiorenzo G. Omenetto  »View Author Affiliations

Optics Express, Vol. 17, Issue 23, pp. 21271-21279 (2009)

View Full Text Article

Enhanced HTML    Acrobat PDF (655 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



We demonstrate controllable structural color based on periodic nanopatterned 2D lattices in pure protein films of silk fibroin. We show here periodic lattices in silk fibroin films with feature sizes of hundreds of nanometers that exhibit different colors as a function of varying lattice spacing. Further, when varying the index of refraction contrast between the nanopatterned lattice and its surrounding environment by applying liquids on top of the lattices, colorimetric shifts are observed. The effect is characterized experimentally and theoretically and a simple example of glucose concentration sensing is presented. This is the first example of a functional sensor based on silk fibroin optics.

© 2009 OSA

OCIS Codes
(160.5470) Materials : Polymers
(220.4000) Optical design and fabrication : Microstructure fabrication
(160.1435) Materials : Biomaterials
(220.4241) Optical design and fabrication : Nanostructure fabrication

ToC Category:

Original Manuscript: August 10, 2009
Revised Manuscript: October 8, 2009
Manuscript Accepted: October 30, 2009
Published: November 6, 2009

Virtual Issues
Vol. 4, Iss. 13 Virtual Journal for Biomedical Optics

Jason J. Amsden, Hannah Perry, Svetlana V. Boriskina, Ashwin Gopinath, David L. Kaplan, Luca Dal Negro, and Fiorenzo G. Omenetto, "Spectral analysis of induced color change on periodically nanopatterned silk films," Opt. Express 17, 21271-21279 (2009)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. H. J. Jin, S. V. Fridrikh, G. C. Rutledge, and D. L. Kaplan, “Electrospinning Bombyx mori silk with poly(ethylene oxide),” Biomacromolecules 3(6), 1233–1239 (2002). [CrossRef] [PubMed]
  2. H.-J. Jin, J. Park, V. Karageorgiou, U. J. Kim, R. Valluzzi, P. Cebe, and D. L. Kaplan, “Water-Stable Silk Films with Reduced β-Sheet Content,” Adv. Funct. Mater. 15(8), 1241–1247 (2005). [CrossRef]
  3. U. J. Kim, J. Park, C. Li, H. J. Jin, R. Valluzzi, and D. L. Kaplan, “Structure and properties of silk hydrogels,” Biomacromolecules 5(3), 786–792 (2004). [CrossRef] [PubMed]
  4. X. Wang, H. J. Kim, P. Xu, A. Matsumoto, and D. L. Kaplan, “Biomaterial coatings by stepwise deposition of silk fibroin,” Langmuir 21(24), 11335–11341 (2005). [CrossRef] [PubMed]
  5. G. H. Altman, F. Diaz, C. Jakuba, T. Calabro, R. L. Horan, J. Chen, H. Lu, J. Richmond, and D. L. Kaplan, “Silk-based biomaterials,” Biomaterials 24(3), 401–416 (2003). [CrossRef] [PubMed]
  6. C. Jiang, X. Wang, R. Gunawidjaja, Y. H. Lin, M. K. Gupta, D. L. Kaplan, R. R. Naik, and V. V. Tsukruk, “Mechanical Properties of Robust Ultrathin Silk Fibroin Films,” Adv. Funct. Mater. 17(13), 2229–2237 (2007). [CrossRef]
  7. T. Xu, N. Zhang, H. L. Nichols, D. Shi, and X. Wen, “Modification of nanostructured materials for biomedical applications,” Mater. Sci. Eng. C 27(3), 579–594 (2007). [CrossRef]
  8. Q. Lv, C. Cao, Y. Zhang, X. Ma, and H. Zhu, “Preparation of insoluble fibroin films without methanol treatment,” J. Appl. Polym. Sci. 96(6), 2168–2173 (2005). [CrossRef]
  9. J. A. Hagen, W. X. Li, H. Spaeth, J. G. Grote, and A. J. Steckl, “Molecular beam deposition of DNA nanometer films,” Nano Lett. 7(1), 133–137 (2007). [CrossRef] [PubMed]
  10. B. D. Lawrence, M. Cronin-Golomb, I. Georgakoudi, D. L. Kaplan, and F. G. Omenetto, “Bioactive silk protein biomaterial systems for optical devices,” Biomacromolecules 9(4), 1214–1220 (2008). [CrossRef] [PubMed]
  11. A. J. Steckl, “DNA - a new material for photonics?” Nat. Photonics 1(1), 3–5 (2007). [CrossRef]
  12. Z. Yu, W. Li, J. A. Hagen, Y. Zhou, D. Klotzkin, J. G. Grote, and A. J. Steckl, “Photoluminescence and lasing from deoxyribonucleic acid (DNA) thin films doped with sulforhodamine,” Appl. Opt. 46(9), 1507–1513 (2007). [CrossRef] [PubMed]
  13. M. K. Gupta, S. K. Khokhar, D. M. Phillips, L. A. Sowards, L. F. Drummy, M. P. Kadakia, and R. R. Naik, “Patterned silk films cast from ionic liquid solubilized fibroin as scaffolds for cell growth,” Langmuir 23(3), 1315–1319 (2007). [CrossRef] [PubMed]
  14. F. G. Omenetto and D. L. Kaplan, “A new route for silk,” Nat. Photonics 2(11), 641–643 (2008). [CrossRef]
  15. H. Perry, A. Gopinath, D. L. Kaplan, L. D. Negro, and F. G. Omenetto, “Nano- and Micropatterning of Optically Transparent, Mechanically Robust, Biocompatible Silk Fibroin Films,” Adv. Mater. 20(16), 3070–3072 (2008). [CrossRef]
  16. S. Sofia, M. B. McCarthy, G. Gronowicz, and D. L. Kaplan, “Functionalized silk-based biomaterials for bone formation,” J. Biomed. Mater. Res. 54(1), 139–148 (2001). [CrossRef] [PubMed]
  17. R. Dallapiccola, A. Gopinath, F. Stellacci, and L. Dal Negro, “Quasi-periodic distribution of plasmon modes in two-dimensional Fibonacci arrays of metal nanoparticles,” Opt. Express 16(8), 5544–5555 (2008). [CrossRef] [PubMed]
  18. A. Gopinath, S. V. Boriskina, N.-N. Feng, B. M. Reinhard, and L. Dal Negro, “Photonic-plasmonic scattering resonances in deterministic aperiodic structures,” Nano Lett. 8(8), 2423–2431 (2008). [CrossRef] [PubMed]
  19. E. G. Loewen, and E. Popov, Diffraction Gratings and Applications (M. Dekker, New York, 1997).
  20. D. W. Mackowski, “Calculation of total cross sections of multiple-sphere clusters,” J. Opt. Soc. Am. A 11(11), 2851–2861 (1994). [CrossRef]
  21. A. Gopinath, S. V. Boriskina, B. M. Reinhard, and L. Dal Negro, “Deterministic aperiodic arrays of metal nanoparticles for surface-enhanced Raman scattering (SERS),” Opt. Express 17(5), 3741–3753 (2009). [CrossRef] [PubMed]
  22. C. A. Browne, A Handbook of Sugar Analysis (John Wiley & Sons, New York, 1912).
  23. C.-S. Cheng, Y.-Q. Chen, and C.-J. Lu, “Organic vapour sensing using localized surface plasmon resonance spectrum of metallic nanoparticles self assemble monolayer,” Talanta 73(2), 358–365 (2007). [CrossRef] [PubMed]
  24. M. D. Malinsky, K. L. Kelly, G. C. Schatz, and R. P. Van Duyne, “Chain Length Dependence and Sensing Capabilities of the Localized Surface Plasmon Resonance of Silver Nanoparticles Chemically Modified with Alkanethiol Self-Assembled Monolayers,” J. Am. Chem. Soc. 123(7), 1471–1482 (2001). [CrossRef]
  25. S. V. Boriskina and L. Dal Negro, “Sensitive label-free biosensing using critical modes in aperiodic photonic structures,” Opt. Express 16(17), 12511–12522 (2008). [CrossRef] [PubMed]
  26. B. Cunningham, J. Qiu, P. Li, and B. Lin, “Enhancing the surface sensitivity of colorimetric resonant optical biosensors,” Sens. Actuators B Chem. 87(2), 365–370 (2002). [CrossRef]
  27. S. Lu, X. Wang, Q. Lu, X. Hu, N. Uppal, F. G. Omenetto, and D. L. Kaplan, “Stabilization of enzymes in silk films,” Biomacromolecules 10(5), 1032–1042 (2009). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3
Fig. 4 Fig. 5

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited