Theoretical analysis of spectrally encoded endoscopy
Optics Express, Vol. 17, Issue 26, pp. 24045-24059 (2009)
http://dx.doi.org/10.1364/OE.17.024045
Enhanced HTML 
Acrobat PDF (1225 KB)
Abstract
Using a single optical fiber and miniature distal optics, spectrally-encoded endoscopy (SEE) has been demonstrated as a promising, three-dimensional endoscopic imaging method with a large number of resolvable points and high frame rates. We present a detailed theoretical study of the SEE prototype system and probe. Several key imaging parameters of SEE are thoroughly derived and formulated, including the three-dimensional point-spread function and field of view, as well as the system’s optical aberrations and fundamental limits. We find that the point-spread function of the SEE system maintains a unique relation between its transverse and axial shapes, discuss the asymmetry of the volumetric field of view, determine that the number of lateral resolvable points is nearly twice than what was previously accepted, and derive an expression for the upper limit for the total number of resolvable points in the cross-sectional image plane.
© 2009 OSA
OCIS Codes
(110.2350) Imaging systems : Fiber optics imaging
(110.2990) Imaging systems : Image formation theory
(110.4850) Imaging systems : Optical transfer functions
(170.2150) Medical optics and biotechnology : Endoscopic imaging
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: August 17, 2009
Revised Manuscript: October 28, 2009
Manuscript Accepted: October 29, 2009
Published: December 17, 2009
Virtual Issues
Vol. 5, Iss. 1 Virtual Journal for Biomedical Optics
Citation
Michal Merman, Avraham Abramov, and Dvir Yelin, "Theoretical analysis of spectrally encoded endoscopy," Opt. Express 17, 24045-24059 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-26-24045
Sort: Year | Journal | Reset
References
- C. M. Brown, P. G. Reinhall, S. Karasawa, and E. J. Seibel, “Optomechanical design and fabrication of resonant microscanners for a scanning fiber endoscope,” Opt. Eng. 45, 043001-043010 (2006). [CrossRef]
- D. L. Dickensheets and G. S. Kino, “Silicon-micromachined scanning confocal optical microscope,” J. Microelectromech. Syst. 7, 38–47 (1998). [CrossRef]
- A. L. Polglase, W. J. McLaren, S. A. Skinner, R. Kiesslich, M. F. Neurath, and P. M. Delaney, “A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract,” in Digestive Disease Week/105th Annual Meeting of the American-Gastroenterological-Association (New Orleans, LA, 2004), pp. 686–695.
- Y. C. Wu, Y. X. Leng, J. F. Xi, and X. D. Li, “Scanning all-fiber-optic endomicroscopy system for 3D nonlinear optical imaging of biological tissues,” Opt. Express 17(10), 7907–7915 (2009). [CrossRef] [PubMed]
- G. J. Tearney, M. Shishkov, and B. E. Bouma, “Spectrally encoded miniature endoscopy,” Opt. Lett. 27(6), 412–414 (2002). [CrossRef] [PubMed]
- D. Yelin, I. Rizvi, W. M. White, J. T. Motz, T. Hasan, B. E. Bouma, and G. J. Tearney, “Three-dimensional miniature endoscopy,” Nature 443(7113), 765 (2006). [CrossRef] [PubMed]
- D. Yelin, S. H. Yun, B. E. Bouma, and G. J. Tearney, “Three-dimensional imaging using spectral encoding heterodyne interferometry,” Opt. Lett. 30(14), 1794–1796 (2005). [CrossRef] [PubMed]
- L. Froehly, S. N. Martin, T. Lasser, C. Depeursinge, and F. Lang, “Multiplexed 3D imaging using wavelength encoded spectral interferometry: a proof of principle,” Opt. Commun. 222, 127–136 (2003). [CrossRef]
- D. Yelin, W. M. White, J. T. Motz, S. H. Yun, B. E. Bouma, and G. J. Tearney, “Spectral-domain spectrally-encoded endoscopy,” Opt. Express 15(5), 2432–2444 (2007). [CrossRef] [PubMed]
- M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, “Sensitivity advantage of swept source and Fourier domain optical coherence tomography,” Opt. Express 11(18), 2183–2189 (2003). [CrossRef] [PubMed]
- J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, “Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,” Opt. Lett. 28(21), 2067–2069 (2003). [CrossRef] [PubMed]
- R. Leitgeb, C. Hitzenberger, and A. Fercher, “Performance of fourier domain vs. time domain optical coherence tomography,” Opt. Express 11(8), 889–894 (2003). [CrossRef] [PubMed]
- D. Yelin, B. E. Bouma, N. Iftimia, and G. J. Tearney, “Three-dimensional spectrally encoded imaging,” Opt. Lett. 28(23), 2321–2323 (2003). [CrossRef] [PubMed]
- D. Yelin, B. E. Bouma, and G. J. Tearney, “Volumetric sub-surface imaging using spectrally encoded endoscopy,” Opt. Express 16(3), 1748–1757 (2008). [CrossRef] [PubMed]
- D. Yelin, B. E. Bouma, J. J. Rosowsky, and G. J. Tearney, “Doppler imaging using spectrally-encoded endoscopy,” Opt. Express 16(19), 14836–14844 (2008). [CrossRef] [PubMed]
- B. E. Bouma, and G. J. Tearney, eds., Handbook of Optical Coherence Tomography (Marcel Dekker, New York, 2002).
- M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, “Full range complex spectral optical coherence tomography technique in eye imaging,” Opt. Lett. 27(16), 1415–1417 (2002). [CrossRef] [PubMed]
- K. B. Sung, C. N. Liang, M. Descour, T. Collier, M. Follen, and R. Richards-Kortum, “Fiber-optic confocal reflectance microscope with miniature objective for in vivo imaging of human tissues,” IEEE Trans. Biomed. Eng. 49(10), 1168–1172 (2002). [CrossRef] [PubMed]
- C. Boudoux, S. Yun, W. Oh, W. White, N. Iftimia, M. Shishkov, B. Bouma, and G. Tearney, “Rapid wavelength-swept spectrally encoded confocal microscopy,” Opt. Express 13(20), 8214–8221 (2005). [CrossRef] [PubMed]
- D. Yelin, C. Boudoux, B. E. Bouma, and G. J. Tearney, “Large area confocal microscopy,” Opt. Lett. 32(9), 1102–1104 (2007). [CrossRef] [PubMed]
- D. Yelin, B. E. Bouma, S. H. Yun, and G. J. Tearney, “Double-clad fiber for endoscopy,” Opt. Lett. 29(20), 2408–2410 (2004). [CrossRef] [PubMed]
Cited By |
 Alert me when this paper is cited |
OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.
Related Journal Articles 
- Optical transfer function analysis of images blurred by nonharmonic vibrations characterized by their power spectrum density (JOSAA)
- Analytical model of a three-dimensional integral image recording system that uses circular- and hexagonal-based spherical surface microlenses (JOSAA)
- Saturated patterned excitation microscopy—a concept for optical resolution improvement (JOSAA)
- New Paradigm for Imaging Systems (AO)
- Three-dimensional optical-transfer-function analysis of fiber-optical two-photon fluorescence microscopy (JOSAA)
Related Conference Papers
- Cr:Forsterite Laser Based Beam-Scanning Multi-Photon Multi-Harmonic Endoscope with Higher Efficiencies
- Ultrathin Fiberscope Utilizing a Single Channel for Both Illumination and Imaging
- 1.6 mm Diameter Scanning Fiber Endoscope
- Dealiased Spectral Images from Aliased Fizeau Fourier Transform Imaging Spectroscopy Measurements
- The application of the ambiguity function to computational imaging
« Previous Article | Next Article »
OSA is a member of 