OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 26 — Dec. 21, 2009
  • pp: 24102–24111

Dynamic micro-bead arrays using optical tweezers combined with intelligent control techniques

Yoshio Tanaka, Hiroyuki Kawada, Shogo Tsutsui, Mitsuru Ishikawa, and Hiroyuki Kitajima  »View Author Affiliations

Optics Express, Vol. 17, Issue 26, pp. 24102-24111 (2009)

View Full Text Article

Enhanced HTML    Acrobat PDF (357 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Dynamic micro-bead arrays offer great flexibility and potential as sensing tools in various scientific fields. Here we present a software-oriented approach for fully automated assembly of versatile dynamic micro-bead arrays using multi-beam optical tweezers combined with intelligent control techniques. Four typical examples, including the collision-free sorting of array elements by bead features, are demonstrated in real time. Control algorithms and experimental apparatus for these demonstrations are also described.

© 2009 OSA

OCIS Codes
(140.7010) Lasers and laser optics : Laser trapping
(150.0150) Machine vision : Machine vision
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4520) Medical optics and biotechnology : Optical confinement and manipulation

ToC Category:
Optical Trapping and Manipulation

Original Manuscript: October 5, 2009
Revised Manuscript: December 3, 2009
Manuscript Accepted: December 4, 2009
Published: December 17, 2009

Virtual Issues
Vol. 5, Iss. 1 Virtual Journal for Biomedical Optics

Yoshio Tanaka, Hiroyuki Kawada, Shogo Tsutsui, Mitsuru Ishikawa, and Hiroyuki Kitajima, "Dynamic micro-bead arrays using optical tweezers combined with intelligent control techniques," Opt. Express 17, 24102-24111 (2009)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. W.-H. Tan and S. Takeuchi, “A trap-and-release integrated microfluidic system for dynamic microarray applications,” Proc. Natl. Acad. Sci. U.S.A. 104(4), 1146–1151 (2007). [CrossRef] [PubMed]
  2. P. Y. Chiou, A. T. Ohta, and M. C. Wu, “Massively parallel manipulation of single cells and microparticles using optical images,” Nature 436(7049), 370–372 (2005). [CrossRef] [PubMed]
  3. H. Noda, Y. Kohara, K. Okano, and H. Kambara, “Automated bead alignment apparatus using a single bead capturing technique for fabrication of a miniaturized bead-based DNA probe array,” Anal. Chem. 75(13), 3250–3255 (2003). [CrossRef] [PubMed]
  4. C. D. Onal and M. Sitti, “Visual servoing-based autonomous 2-D manipulation of microparticles using a nanoprobe,” IEEE Trans. Contr. Syst. Technol. 15(5), 842–852 (2007). [CrossRef]
  5. A. Ashkin, J. M. Dziedzic, J. E. Bjorkholm, and S. Chu, “Observation of a single-beam gradient force optical trap for dielectric particles,” Opt. Lett. 11(5), 288–290 (1986). [CrossRef] [PubMed]
  6. D. G. Grier, “A revolution in optical manipulation,” Nature 424(6950), 810–816 (2003). [CrossRef] [PubMed]
  7. J. E. Curtis, B. A. Koss, and D. G. Grier, “Dynamic holographic optical tweezers,” Opt. Commun. 207(1-6), 169–175 (2002). [CrossRef]
  8. P. J. Rodrigo, R. L. Eriksen, V. R. Daria, and J. Glueckstad, “Interactive light-driven and parallel manipulation of inhomogeneous particles,” Opt. Express 10(26), 1550–1556 (2002). [PubMed]
  9. C. Mio and D. W. M. Marr, “Optical trapping for the manipulation of colloidal particles,” Adv. Mater. 12(12), 917–920 (2000). [CrossRef]
  10. J. M. Tam, I. Biran, and D. R. Walt; “An imaging fiber-based optical tweezer array for microparticle array assembly,” Appl. Phys. Lett. 84(21), 4289–4291 (2004). [CrossRef]
  11. D. H. Ballard, and C. M. Brown, Computer Vision (Prentice-Hall, 1982), Chap. 3–4.
  12. J. Chen, Group Representation Theory for Physicists (World Scientific, 1989), Chap. 1.
  13. Y. Tanaka, H. Kawada, K. Hirano, M. Ishikawa, and H. Kitajima, Japan patent 2008–101060 (April, 9, 2008).
  14. http://www.rubiks.com/
  15. Y. Tanaka, H. Kawada, K. Hirano, M. Ishikawa, and H. Kitajima, “Automated manipulation of non-spherical micro-objects using optical tweezers combined with image processing techniques,” Opt. Express 16(19), 15115–15122 (2008). [CrossRef] [PubMed]
  16. S. C. Chapin, V. Germain, and E. R. Dufresne, “Automated trapping, assembly, and sorting with holographic optical tweezers,” Opt. Express 14(26), 13095–13100 (2006). [CrossRef] [PubMed]
  17. Y. Tanaka, K. Hirano, H. Nagata, and M. Ishikawa, “Real-time three-dimensional orientation control of non-spherical micro-objects using laser trapping,” Electron. Lett. 43(7), 412–414 (2007). [CrossRef]
  18. N. Otsu, “A threshold selection method from gray-level histograms,” IEEE Trans. Sys., Man, Cybernetics SMC-9, 62–66 (1979).
  19. A. Murakami, Y. Tanaka, and Y. Kinouch, “Laser manipulation system for automatic control of microscopic particles,” in Proceedings of the 4th Asian Control Conference, Singapore, 25–27 Sept. 2002, pp.414–419.
  20. G. S. Sinclair, P. Jordan, J. Courtial, M. Padgett, J. Cooper, and Z. J. Laczik, “Assembly of 3-dimensional structures using programmable holographic optical tweezers,” Opt. Express 12(22), 5475–5480 (2004). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Supplementary Material

» Media 1: MOV (1740 KB)     
» Media 2: MOV (1860 KB)     
» Media 3: MOV (1435 KB)     
» Media 4: MOV (1485 KB)     

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited