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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 3 — Feb. 2, 2009
  • pp: 1372–1384

A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes

Justin Y. Lo, Bing Yu, Henry L. Fu, Janelle E. Bender, Gregory M. Palmer, Thomas F. Kuech, and Nirmala Ramaimjam  »View Author Affiliations


Optics Express, Vol. 17, Issue 3, pp. 1372-1384 (2009)
http://dx.doi.org/10.1364/OE.17.001372


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Abstract

A diffuse reflectance spectroscopy system was modified as a step towards miniaturization and spectral imaging of tissue absorption and scattering. The modified system uses a tunable source and an optical fiber for illumination and a photodiode in contact with tissue for detection. Compared to the previous system, it is smaller, less costly, and has comparable performance in extracting optical properties in tissue phantoms. Wavelength reduction simulations show the feasibility of replacing the source with LEDs to further decrease system size and cost. Simulated crosstalk analysis indicates that this evolving system can be multiplexed for spectral imaging in the future.

© 2009 Optical Society of America

OCIS Codes
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 28, 2008
Revised Manuscript: January 15, 2009
Manuscript Accepted: January 16, 2009
Published: January 22, 2009

Virtual Issues
Vol. 4, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Justin Y. Lo, Bing Yu, Henry L. Fu, Janelle E. Bender, Gregory M. Palmer, Thomas F. Kuech, and Nirmala Ramanujam, "A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes," Opt. Express 17, 1372-1384 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-3-1372


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