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Optics Express

Optics Express

| THE INTERNATIONAL ELECTRONIC JOURNAL OF OPTICS

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 5 — Mar. 2, 2009
  • pp: 4019–4036

Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography

Madhusudhanan Balasubramanian, Christopher Bowd, Gianmarco Vizzeri, Robert N. Weinreb, and Linda M. Zangwill

Optics Express, Vol. 17, Issue 5, pp. 4019-4036        doi:10.1364/OE.17.004019

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  • OCIS Codes:
  • (110.4500) Imaging systems : Optical coherence tomography
  • (170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

Citation
Madhusudhanan Balasubramanian, Christopher Bowd, Gianmarco Vizzeri, Robert N. Weinreb, and Linda M. Zangwill, "Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography," Opt. Express 17, 4019-4036 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-4019

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Abstract

The purpose of this study was to investigate the effect of image quality on retinal nerve fiber layer (RNFL) and retinal thickness measurements obtained using three commercially available spectral domain-optical coherence tomographers (SD-OCT). Subjectively determined good, medium and poor quality images were obtained from four healthy and one glaucoma suspect eyes. RNFL and retinal thickness measurements were compared as a function of image quality. Results indicate that when image quality is within the range specified as acceptable by SD-OCT manufacturers, RNFL and retinal thickness measurements are comparable.

© 2009 Optical Society of America

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History
Original Manuscript: October 17, 2008
Manuscript Accepted: February 19, 2009
Revised Manuscript: January 17, 2009
Published: March 2, 2009

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Author Affiliations

Madhusudhanan Balasubramanian, Christopher Bowd, Gianmarco Vizzeri, Robert N. Weinreb

Hamilton Glaucoma Center, Department of Ophthalmology, University of California San Diego

Linda M. Zangwill

University of California San Diego

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