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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 5 — Mar. 2, 2009
  • pp: 4084–4094

Cellular resolution volumetric in vivo retinal imaging with adaptive optics–optical coherence tomography

Robert J. Zawadzki, Stacey S. Choi, Alfred R. Fuller, Julia W. Evans, Bernd Hamann, and John S. Werner  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 4084-4094 (2009)
http://dx.doi.org/10.1364/OE.17.004084


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Abstract

Ultrahigh-resolution adaptive optics–optical coherence tomography (UHR-AO-OCT) instrumentation allowing monochromatic and chromatic aberration correction was used for volumetric in vivo retinal imaging of various retinal structures including the macula and optic nerve head (ONH). Novel visualization methods that simplify AO-OCT data viewing are presented, and include co-registration of AO-OCT volumes with fundus photography and stitching of multiple AO-OCT sub-volumes to create a large field of view (FOV) high-resolution volume. Additionally, we explored the utility of Interactive Science Publishing by linking all presented AO-OCT datasets with the OSA ISP software.

© 2009 Optical Society of America

OCIS Codes
(010.1080) Atmospheric and oceanic optics : Active or adaptive optics
(110.4500) Imaging systems : Optical coherence tomography
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.0110) Medical optics and biotechnology : Imaging systems
(170.4470) Medical optics and biotechnology : Ophthalmology
(220.1000) Optical design and fabrication : Aberration compensation

ToC Category:
OCT Technology

History
Original Manuscript: August 22, 2008
Revised Manuscript: February 11, 2009
Manuscript Accepted: February 11, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Robert J. Zawadzki, Stacey S. Choi, Alfred R. Fuller, Julia W. Evans, Bernd Hamann, and John S. Werner, "Cellular resolution volumetric in vivo retinal imaging with adaptive optics–optical coherence tomography," Opt. Express 17, 4084-4094 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-4084


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