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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 5 — Mar. 2, 2009
  • pp: 4112–4133

Multidimensional en-Face OCT imaging of the retina

Richard B. Rosen, Mark Hathaway, John Rogers, Justin Pedro, Patricia Garcia, Philippe Laissue, George M. Dobre, and Adrian Gh. Podoleanu  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 4112-4133 (2009)
http://dx.doi.org/10.1364/OE.17.004112


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Abstract

Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images of the fundus and B-scan OCT images. Benefits in combining T-scan OCT with confocal imaging to generate pairs of OCT and confocal images similar to those generated by scanning laser ophthalmoscopy (SLO) are discussed in comparison with the spectral OCT systems. The multichannel potential of the OCT/SLO system is demonstrated with the addition of a third hardware channel which acquires and generates indocyanine green (ICG) fluorescence images. The OCT, confocal SLO and ICG fluorescence images are simultaneously presented in a two or a three screen format. A fourth channel which displays a live mix of frames of the ICG sequence superimposed on the corresponding coronal OCT slices for immediate multidimensional comparison, is also included. OSA ISP software is employed to illustrate the synergy between the simultaneously provided perspectives. This synergy promotes interpretation of information by enhancing diagnostic comparisons and facilitates internal correction of movement artifacts within C-scan and B-scan OCT images using information provided by the SLO channel.

© 2009 Optical Society of America

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
OCT Technology

History
Original Manuscript: October 1, 2008
Revised Manuscript: January 15, 2009
Manuscript Accepted: January 15, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Richard B. Rosen, Mark Hathaway, John Rogers, Justin Pedro, Patricia Garcia, Philippe Laissue, George M. Dobre, and Adrian G. Podoleanu, "Multidimensional en-Face OCT imaging of the retina," Opt. Express 17, 4112-4133 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-4112


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