OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 1 — Jan. 4, 2010
  • pp: 25–30

An in vivo study of turbidity suppression by optical phase conjugation (TSOPC) on rabbit ear

Meng Cui, Emily J. McDowell, and Changhuei Yang  »View Author Affiliations

Optics Express, Vol. 18, Issue 1, pp. 25-30 (2010)

View Full Text Article

Enhanced HTML    Acrobat PDF (390 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



We present a holography-based in vivo optical phase conjugation experiment performed on a living rabbit ear. The motion of live tissues caused the phase conjugate signal to decay with a consistent decay time of less than two seconds. We monitor the signal decay time variation after the ear is excised to postulate different mechanisms that cause the signal decay. The experimental findings address the minimum speed limit of a broad range of optical time reversal experiments for in vivo applications on tissues.

© 2009 OSA

OCIS Codes
(090.1000) Holography : Aberration compensation
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6930) Medical optics and biotechnology : Tissue
(170.7050) Medical optics and biotechnology : Turbid media
(170.6935) Medical optics and biotechnology : Tissue characterization

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: October 5, 2009
Revised Manuscript: December 11, 2009
Manuscript Accepted: December 11, 2009
Published: December 22, 2009

Virtual Issues
Vol. 5, Iss. 2 Virtual Journal for Biomedical Optics

Meng Cui, Emily J. McDowell, and Changhuei Yang, "An in vivo study of turbidity suppression by optical phase conjugation (TSOPC) on rabbit ear," Opt. Express 18, 25-30 (2010)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. T. Vo-Dinh, Biomedical photonics handbook (CRC press, New York, 2003).
  2. V. V. Tuchin, “Optical clearing of tissues and blood using the immersion method,” J. Phys. D Appl. Phys. 38(15), 2497–2518 (2005). [CrossRef]
  3. I. M. Vellekoop and A. P. Mosk, “Universal optimal transmission of light through disordered materials,” Phys. Rev. Lett. 101(12), 120601 (2008). [CrossRef] [PubMed]
  4. A. Yariv and P. Yeh, “Phase conjugate optics and real-time holography,” IEEE J. Quantum Electron. 14(9), 650–660 (1978). [CrossRef]
  5. J. Feinberg and R. W. Hellwarth, “Phase-conjugating mirror with continuous-wave gain,” Opt. Lett. 5(12), 519–521 (1980). [CrossRef] [PubMed]
  6. R. C. Lind and D. G. Steel, “Demonstration of the longitudinal modes and aberrationcorrection properties of a continuous-wave dye laser with a phase-conjugate mirror,” Opt. Lett. 6(11), 554–556 (1981). [CrossRef] [PubMed]
  7. P. D. Drummond and A. T. Friberg, “Specular reflection cancellation in an interferometer with a phase-conjugate mirror,” J. Appl. Phys. 54(10), 5618–5625 (1983). [CrossRef]
  8. D. P. M. Gower, Optical phase conjugation (Springer-Verlag, New York, 1994).
  9. Z. Yaqoob, D. Psaltis, M. S. Feld, and C. Yang, “Optical phase conjugation for turbidity suppression in biological samples,” Nat. Photonics 2(2), 110–115 (2008). [CrossRef] [PubMed]
  10. E. J. McDowell, M. Cui, I. M. Vellekoop, V. Senekerimyan, and Z. Yaqoob, “Turbidity suppression from the ballistic to the diffusice regime in biological tissues using optical phase conjugation,” J. Biomed. Opt. submitted. [PubMed]
  11. K. Jeong, J. J. Turek, and D. D. Nolte, “Volumetric motility-contrast imaging of tissue response to cytoskeletal anti-cancer drugs,” Opt. Express 15(21), 14057–14064 (2007). [CrossRef] [PubMed]
  12. C. Gu and P. C. Yeh, “Partial phase-conjugation, fidelity, and reciprocity,” Opt. Commun. 107(5-6), 353–357 (1994). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited