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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 12 — Jun. 7, 2010
  • pp: 12960–12970

Optics InfoBase > Optics Express > Volume 18 > Issue 12 > Page 12960

Small-angle scattering computed tomography (SAS-CT) using a Talbot-Lau interferometer
and a rotating anode x-ray tube:
theory and experiments

Guang-Hong Chen, Nicholas Bevins, Joseph Zambelli, and Zhihua Qi  »View Author Affiliations


Optics Express, Vol. 18, Issue 12, pp. 12960-12970 (2010)
http://dx.doi.org/10.1364/OE.18.012960


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Abstract

X-ray differential phase contrast imaging methods, including projection imaging and the corresponding computed tomography (CT), have been implemented using a Talbot interferometer and either a synchrotron beam line or a low brilliance x-ray source generated by a stationary-anode x-ray tube. From small-angle scattering events which occur as an x-ray propagates through a medium, a signal intensity loss can be recorded and analyzed for an understanding of the micro-structures in an image object. This has been demonstrated using a Talbot-Lau interferometer and a stationary-anode x-ray tube. In this paper, theoretical principles and an experimental implementation of the corresponding CT imaging method are presented. First, a line integral is derived from analyzing the cross section of the small-angle scattering events. This method is referred to as small-angle scattering computed tomography (SAS-CT). Next, a Talbot-Lau interferometer and a rotating-anode x-ray tube were used to implement SAS-CT. A physical phantom and human breast tissue sample were used to demonstrate the reconstructed SAS-CT image volumes.

© 2010 OSA

OCIS Codes
(050.1950) Diffraction and gratings : Diffraction gratings
(110.6760) Imaging systems : Talbot and self-imaging effects
(290.0290) Scattering : Scattering
(340.7440) X-ray optics : X-ray imaging
(340.7450) X-ray optics : X-ray interferometry
(110.3010) Imaging systems : Image reconstruction techniques

ToC Category:
X-ray Optics

History
Original Manuscript: March 22, 2010
Revised Manuscript: May 3, 2010
Manuscript Accepted: May 30, 2010
Published: June 2, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Guang-Hong Chen, Nicholas Bevins, Joseph Zambelli, and Zhihua Qi, "Small-angle scattering computed tomography (SAS-CT) using a Talbot-Lau interferometer
and a rotating anode x-ray tube:
theory and experiments," Opt. Express 18, 12960-12970 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-12-12960


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