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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 16 — Aug. 2, 2010
  • pp: 17392–17403

Real time, nanometric 3D-tracking of nanoparticles made possible by second harmonic generation digital holographic microscopy

Etienne Shaffer, Pierre Marquet, and Christian Depeursinge  »View Author Affiliations


Optics Express, Vol. 18, Issue 16, pp. 17392-17403 (2010)
http://dx.doi.org/10.1364/OE.18.017392


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Abstract

In the past decade, quantitative phase imaging gave a new dimension to optical microscopy, and the recent extension of digital holography techniques to nonlinear microscopy appears very promising, for the phase of nonlinear signal provides additional information, inaccessible to incoherent imaging schemes. In this work, we show that the position of second harmonic generation (SHG) emitters can be determined from their respective phase, at the nanometer scale, with single-shot off-axis digital holography, making possible real-time nanometric 3D-tracking of SHG emitters such as nanoparticles.

© 2010 Optical Society of America

OCIS Codes
(090.1995) Holography : Digital holography
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:
Microscopy

History
Original Manuscript: April 28, 2010
Revised Manuscript: June 28, 2010
Manuscript Accepted: July 21, 2010
Published: July 30, 2010

Virtual Issues
Vol. 5, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Etienne Shaffer, Pierre Marquet, and Christian Depeursinge, "Real time, nanometric 3D-tracking of nanoparticles made possible by second harmonic generation digital holographic microscopy," Opt. Express 18, 17392-17403 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-16-17392


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