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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 19 — Sep. 13, 2010
  • pp: 19444–19455

Contrast and resolution analysis of iterative angular domain optical projection tomography

Eldon Ng, Fartash Vasefi, Bozena Kaminska, Glenn H. Chapman, and Jeffrey J.L. Carson  »View Author Affiliations

Optics Express, Vol. 18, Issue 19, pp. 19444-19455 (2010)

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In Angular Domain Imaging, image contrast and resolution are position dependent. The objective of this work was to characterize the contrast and resolution of an ADI system at a multitude of locations within the imaging plane, then compare the reconstructions of different targets using filtered back projection and iterative reconstruction algorithms. Contrast varied significantly with depth and minimally with lateral position, while resolution varied significantly with lateral position and minimally with depth. The iterative reconstruction algorithm was robust against ring and streak artifacts. The back projection reconstructions suffered from artifacts related to a lack of projection data.

© 2010 OSA

OCIS Codes
(100.6950) Image processing : Tomographic image processing
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(110.0113) Imaging systems : Imaging through turbid media
(110.6955) Imaging systems : Tomographic imaging

ToC Category:
Imaging Systems

Original Manuscript: April 9, 2010
Revised Manuscript: July 25, 2010
Manuscript Accepted: August 20, 2010
Published: August 30, 2010

Virtual Issues
Vol. 5, Iss. 13 Virtual Journal for Biomedical Optics

Eldon Ng, Fartash Vasefi, Bozena Kaminska, Glenn H. Chapman, and Jeffrey J. L. Carson, "Contrast and resolution analysis of iterative angular domain optical projection tomography," Opt. Express 18, 19444-19455 (2010)

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  1. J. Sharpe, “Optical projection tomography as a new tool for studying embryo anatomy,” J. Anat. 202(2), 175–181 (2003). [CrossRef] [PubMed]
  2. G. Yoon, A. Welch, M. Motamedi, and M. Gemert, “Development and application of three-dimensional light distribution model for laser irradiated tissue,” IEEE J. Quantum Electron. 23(10), 1721–1733 (1987). [CrossRef]
  3. M. A. O’Leary, D. A. Boas, B. Chance, and A. G. Yodh, “Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography,” Opt. Lett. 20(5), 426–428 (1995). [CrossRef] [PubMed]
  4. K. Chen, L. T. Perelman, Q. Zhang, R. R. Dasari, and M. S. Feld, “Optical computed tomography in a turbid medium using early arriving photons,” J. Biomed. Opt. 5(2), 144–154 (2000). [CrossRef] [PubMed]
  5. W. Cai, S. K. Gayen, M. Xu, M. Zevallos, M. Alrubaiee, M. Lax, and R. R. Alfano, “Optical tomographic image reconstruction from ultrafast time-sliced transmission measurements,” Appl. Opt. 38(19), 4237–4246 (1999). [CrossRef]
  6. M. Niedre and V. Ntziachristos, “Comparison of fluorescence tomographic imaging in mice with early-arriving and quasi-continuous-wave photons,” Opt. Lett. 35(3), 369–371 (2010). [CrossRef] [PubMed]
  7. F. Vasefi, E. Ng, B. Kaminska, G. H. Chapman, K. Jordan, and J. J. L. Carson, “Transmission and fluorescence angular domain optical projection tomography of turbid media,” Appl. Opt. 48(33), 6448–6457 (2009). [CrossRef] [PubMed]
  8. A. C. Boccara, “Imaging through scattering media,” in Encyclopedia of Modern Optics, (Academic Press, 2004).
  9. G. H. Chapman, M. Trinh, N. Pfeiffer, G. Chu, and D. Lee, “Angular domain imaging of objects within highly scattering media using silicon micromachined collimating arrays,” IEEE J. Sel. Top. Quantum Electron. 9(2), 257–266 (2003). [CrossRef]
  10. F. Vasefi, B. Kaminska, G. H. Chapman, and J. J. L. Carson, “Angular distribution of quasi-ballistic light measured through turbid media using angular domain optical imaging” Proc. SPIE 7175, (2009).
  11. F. Vasefi, B. S. L. Hung, B. Kaminska, G. H. Chapman, and J. J. L. Carson, “Angular domain optical imaging of turbid media using enhanced micro-tunnel filter arrays” Proc. SPIE 7369, (2009).
  12. F. Vasefi, M. Najiminaini, E. Ng, B. Kaminska, G. H. Chapman, and J. J. L. Carson, “Angular domain trans-illumination imaging optimization with an ultra-fast gated camera,” J. Biomed. Opt. (to be published). [PubMed]
  13. V. Ntziachristos, J. Ripoll, L. V. Wang, and R. Weissleder, “Looking and listening to light: the evolution of whole-body photonic imaging,” Nat. Biotechnol. 23(3), 313–320 (2005). [CrossRef] [PubMed]
  14. R. Michels, F. Foschum, and A. Kienle, “Optical properties of fat emulsions,” Opt. Express 16(8), 5907–5925 (2008). [CrossRef] [PubMed]
  15. S. T. Flock, S. L. Jacques, B. C. Wilson, W. M. Star, and M. J. van Gemert, “Optical properties of Intralipid: a phantom medium for light propagation studies,” Lasers Surg. Med. 12(5), 510–519 (1992). [CrossRef] [PubMed]
  16. E. Ng, F. Vasefi, B. Kaminska, G. H. Chapman, and J. J. L. Carson, “Contrast and resolution analysis of angular domain imaging for iterative optical projection tomography reconstruction” Proc. SPIE 7557, (2010).
  17. J. C. Hebden, “Evaluating the spatial resolution performance of a time-resolved optical imaging system,” Med. Phys. 19(4), 1081–1087 (1992). [CrossRef] [PubMed]
  18. F. Vasefi, B. Kaminska, G. H. Chapman, and J. J. L. Carson, “Image contrast enhancement in angular domain optical imaging of turbid media,” Opt. Express 16(26), 21492–21504 (2008). [CrossRef] [PubMed]

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