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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 22 — Oct. 25, 2010
  • pp: 22702–22714

Sensitivity enhancement in photonic crystal slab biosensors

Mohamed El Beheiry, Victor Liu, Shanhui Fan, and Ofer Levi  »View Author Affiliations


Optics Express, Vol. 18, Issue 22, pp. 22702-22714 (2010)
http://dx.doi.org/10.1364/OE.18.022702


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Abstract

Refractive index sensitivity of guided resonances in photonic crystal slabs is analyzed. We show that modal properties of guided resonances strongly affect spectral sensitivity and quality factors, resulting in substantial enhancement of refractive index sensitivity. A three-fold spectral sensitivity enhancement is demonstrated for suspended slab designs, in contrast to designs with a slab resting over a substrate. Spectral sensitivity values are additionally shown to be unaffected by quality factor reductions, which are common to fabricated photonic crystal nano-structures. Finally, we determine that proper selection of photonic crystal slab design parameters permits biosensing of a wide range of analytes, including proteins, antigens, and cells. These photonic crystals are compatible with large-area biosensor designs, permitting direct access to externally incident optical beams in a microfluidic device.

© 2010 OSA

OCIS Codes
(130.2790) Integrated optics : Guided waves
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(050.5298) Diffraction and gratings : Photonic crystals

ToC Category:
Photonic Crystals

History
Original Manuscript: July 19, 2010
Revised Manuscript: September 7, 2010
Manuscript Accepted: September 20, 2010
Published: October 12, 2010

Virtual Issues
Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Mohamed El Beheiry, Victor Liu, Shanhui Fan, and Ofer Levi, "Sensitivity enhancement in photonic crystal slab biosensors," Opt. Express 18, 22702-22714 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-22-22702


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