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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 24 — Nov. 22, 2010
  • pp: 24565–24578

Experimental demonstration of an Optical-Sectioning Compressive Sensing Microscope (CSM)

Yuehao Wu, Peng Ye, Iftekhar O. Mirza, Gonzalo R. Arce, and Dennis W. Prather  »View Author Affiliations

Optics Express, Vol. 18, Issue 24, pp. 24565-24578 (2010)

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In this paper we present the design and implementation of a Compressive Sensing Microscopy (CSM) imaging system, which uses the Compressive Sensing (CS) method to realize optical-sectioning imaging. The theoretical aspect of the proposed system is investigated using the mathematical model of the CS method and an experimental prototype is constructed to verify the CSM design. Compared to conventional optical-sectioning microscopes (such as Laser Scanning Confocal Microscopes (LSCMs) or Programmable Array Microscopes (PAMs)), the CSM system realizes optical-sectioning imaging using a single-pixel photo detector and without any mechanical scanning process. The complete information of the imaging scene is reconstructed from the CS measurements numerically.

© 2010 OSA

OCIS Codes
(110.0110) Imaging systems : Imaging systems
(180.1790) Microscopy : Confocal microscopy
(180.2520) Microscopy : Fluorescence microscopy

ToC Category:

Original Manuscript: August 9, 2010
Revised Manuscript: October 13, 2010
Manuscript Accepted: October 30, 2010
Published: November 10, 2010

Yuehao Wu, Peng Ye, Iftekhar O. Mirza, Gonzalo R. Arce, and Dennis W. Prather, "Experimental demonstration of an Optical-Sectioning Compressive Sensing Microscope (CSM)," Opt. Express 18, 24565-24578 (2010)

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