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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 26 — Dec. 20, 2010
  • pp: 27560–27566

Fabrication of glucose fiber sensor based on immobilized GOD technique for rapid measurement

Ting-Qian Lin, Yin-Lin Lu, and Cheng-Chih Hsu  »View Author Affiliations


Optics Express, Vol. 18, Issue 26, pp. 27560-27566 (2010)
http://dx.doi.org/10.1364/OE.18.027560


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Abstract

The concentration and pH value of the immobilized glucose oxidase (GOD) are critical parameters in a glucose sensor. In this study, we develop a glucose fiber sensor integrated with heterodyne interferometry to measure the phase difference arising from the chemical reaction between glucose and GOD. Our studies show that the response time and resolution of this sensor will be strongly affected by the pH and concentration properties of GOD. In addition, the results show good linearity between the calibration curve for the glucose solution and serum based sample. The response time of this sensor can be shorter than 3 seconds and best resolutions are 0.1 and 0.136 mg/dl for glucose solution and serum based sample, respectively.

© 2010 OSA

OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(280.4788) Remote sensing and sensors : Optical sensing and sensors

ToC Category:
Sensors

History
Original Manuscript: September 30, 2010
Revised Manuscript: November 10, 2010
Manuscript Accepted: November 11, 2010
Published: December 15, 2010

Citation
Ting-Qian Lin, Yin-Lin Lu, and Cheng-Chih Hsu, "Fabrication of glucose fiber sensor based on immobilized GOD technique for rapid measurement," Opt. Express 18, 27560-27566 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-26-27560


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References

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