## Multilevel bioluminescence tomography based on radiative transfer equation Part 1: l1 regularization

Optics Express, Vol. 18, Issue 3, pp. 1854-1871 (2010)

http://dx.doi.org/10.1364/OE.18.001854

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### Abstract

In this paper we study an l1-regularized multilevel approach for bioluminescence tomography based on radiative transfer equation with the emphasis on improving imaging resolution and reducing computational time. Simulations are performed to validate that our algorithms are potential for efficient high-resolution imaging. Besides, we study and compare reconstructions with boundary angular-averaged data, boundary angular-resolved data and internal angular-averaged data respectively.

© 2010 OSA

**OCIS Codes**

(100.3190) Image processing : Inverse problems

(110.6960) Imaging systems : Tomography

(170.3010) Medical optics and biotechnology : Image reconstruction techniques

(170.6280) Medical optics and biotechnology : Spectroscopy, fluorescence and luminescence

**ToC Category:**

Medical Optics and Biotechnology

**History**

Original Manuscript: October 12, 2009

Revised Manuscript: November 18, 2009

Manuscript Accepted: January 2, 2010

Published: January 15, 2010

**Virtual Issues**

Vol. 5, Iss. 4 *Virtual Journal for Biomedical Optics*

**Citation**

Hao Gao and Hongkai Zhao, "Multilevel bioluminescence tomography based on radiative transfer equation Part 1: l1 regularization," Opt. Express **18**, 1854-1871 (2010)

http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-3-1854

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