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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 4 — Feb. 15, 2010
  • pp: 3244–3257

Use of a multi-spectral camera in the characterization of skin wounds

Ali Basiri, Marjan Nabili, Scott Mathews, Alex Libin, Suzanne Groah, Herke J. Noordmans, and Jessica C. Ramella-Roman  »View Author Affiliations

Optics Express, Vol. 18, Issue 4, pp. 3244-3257 (2010)

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Skin breakdown is a prevalent and costly medical condition worldwide, with the etiologic and healing processes being complex and multifactorial. Quantitative assessment of wound healing is challenging due to the subjective measurement of wound size and related characteristics. We propose that in vivo spectral reflectance measurements can serve as valuable clinical monitoring tool/device in the study of wound healing. We have designed a multi spectral camera able to acquire 18 wavelength sensitive images in a single snapshot. A lenslets array in front of a digital camera is combined with narrowband filters (bandwidth 10 nm) ranging from 460 to 886nm. Images taken with the spectroscopic camera are composed of 18 identical sub-images, each carrying different spectral information, that can be used in the assessment of skin chromophores. A clinical trial based on a repeated measures design was conducted at the National Rehabilitation Hospital on 15 individuals to assess whether Poly Carboxy Methyl Glucose Sulfate (PCMGS, CACIPLIQ20), a bio-engineered component of the extracellular matrix of the skin, is effective at promoting healing of a variety of wounds. Multi spectral images collected at different wavelengths combined with optical skin models were used to quantify skin oxygen saturation and its relation to the traditional measures of wound healing.

© 2010 OSA

OCIS Codes
(170.1870) Medical optics and biotechnology : Dermatology
(110.4234) Imaging systems : Multispectral and hyperspectral imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: October 29, 2009
Revised Manuscript: January 13, 2010
Manuscript Accepted: January 14, 2010
Published: February 1, 2010

Virtual Issues
Vol. 5, Iss. 5 Virtual Journal for Biomedical Optics

Ali Basiri, Marjan Nabili, Scott Mathews, Alex Libin, Suzanne Groah, Herke J. Noordmans, and Jessica C. Ramella-Roman, "Use of a multi-spectral camera in the characterization of skin wounds," Opt. Express 18, 3244-3257 (2010)

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