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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 4 — Feb. 15, 2010
  • pp: 3967–3972

Photoacoustic ophthalmoscopy for in vivo retinal imaging

Shuliang Jiao, Minshan Jiang, Jianming Hu, Amani Fawzi, Qifa Zhou, K. Kirk Shung, Carmen A. Puliafito, and Hao F. Zhang  »View Author Affiliations

Optics Express, Vol. 18, Issue 4, pp. 3967-3972 (2010)

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We have developed a non-invasive photoacoustic ophthalmoscopy (PAOM) for in vivo retinal imaging. PAOM detects the photoacoustic signal induced by pulsed laser light shined onto the retina. By using a stationary ultrasonic transducer in contact with the eyelids and scanning only the laser light across the retina, PAOM provides volumetric imaging of the retinal micro-vasculature and retinal pigment epithelium at a high speed. For B-scan frames containing 256 A-lines, the current PAOM has a frame rate of 93 Hz, which is comparable with state-of-the-art commercial spectral-domain optical coherence tomography (SD-OCT). By integrating PAOM with SD-OCT, we further achieved OCT-guided PAOM, which can provide multi-modal retinal imaging simultaneously. The capabilities of this novel technology were demonstrated by imaging both the microanatomy and microvasculature of the rat retina in vivo.

© 2010 OSA

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: December 22, 2009
Revised Manuscript: January 27, 2010
Manuscript Accepted: February 1, 2010
Published: February 12, 2010

Virtual Issues
Vol. 5, Iss. 5 Virtual Journal for Biomedical Optics

Shuliang Jiao, Minshan Jiang, Jianming Hu, Amani Fawzi, Qifa Zhou, K. Kirk Shung, Carmen A. Puliafito, and Hao F. Zhang, "Photoacoustic ophthalmoscopy for in vivo retinal imaging," Opt. Express 18, 3967-3972 (2010)

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