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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 8 — Apr. 12, 2010
  • pp: 8151–8159

RECIST versus volume measurement in medical CT using ellipsoids of known size

Zachary H. Levine, Bruce R. Borchardt, Nolan J. Brandenburg, Charles W. Clark, Bala Muralikrishnan, Craig M. Shakarji, Joseph J. Chen, and Eliot L. Siegel  »View Author Affiliations

Optics Express, Vol. 18, Issue 8, pp. 8151-8159 (2010)

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Two hundred eighty three uniaxial ellipsoids with sizes from 4 mm to 11 mm were measured with a coordinate measuring matching (CMM) and also scanned using a medical computed tomography (CT) machine. Their volumes were determined by counting voxels over a threshold, as well as using equivalent volumes from the length given by the RECIST 1.1 criterion (Response Evaluation Criteria in Solid Tumors). The volumetric measurements yield an order of magnitude reduction in residuals compared to the CMM measurements than the residuals of the RECIST measurements also compared to the CMM measurements.

© 2010 OSA

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.7440) Medical optics and biotechnology : X-ray imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 18, 2009
Revised Manuscript: December 22, 2009
Manuscript Accepted: February 8, 2010
Published: April 1, 2010

Virtual Issues
Vol. 5, Iss. 8 Virtual Journal for Biomedical Optics
Imaging in Diagnosis and Treatment of Lung Cancer (2010) Optics Express

Zachary H. Levine, Bruce R. Borchardt, Nolan J. Brandenburg, Charles W. Clark, Bala Muralikrishnan, Craig M. Shakarji, Joseph J. Chen, and Eliot L. Siegel, "RECIST versus volume measurement in medical CT using ellipsoids of known size," Opt. Express 18, 8151-8159 (2010)

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  1. E. A. Eisenhauer, P. Therasse, J. Bogaerts, L. H. Schwartz, D. Sargent, R. Ford, J. Dancey, S. Arbuck, S. Gwyther, M. Mooney, L. Rubinstein, L. Shankar, L. Dodd, R. Kaplan, D. Lacombe, J. Verweij, and J. Verweij, “New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1),” Eur. J. Cancer 45(2), 228–247 (2009). [CrossRef]
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