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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 19, Iss. 11 — May. 23, 2011
  • pp: 10153–10163

Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry

Chunhui Li, Zhihong Huang, and Ruikang K. Wang  »View Author Affiliations


Optics Express, Vol. 19, Issue 11, pp. 10153-10163 (2011)
http://dx.doi.org/10.1364/OE.19.010153


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Abstract

Advances in the field of laser ultrasonics have opened up new possibilities in medical applications. This paper evaluates this technique as a method that would allow for rapid characterization of the elastic properties of soft biological tissue. In doing so, we propose a novel approach that utilizes a low coherence interferometer to detect the laser-induced surface acoustic waves (SAW) from the tissue-mimicking phantoms. A Nd:YAG focused laser line-source is applied to one- and two-layer tissue-mimicking agar-agar phantoms, and the generated SAW signals are detected by a time domain low coherence interferometry system. SAW phase velocity dispersion curves are calculated, from which the elasticity of the specimens is evaluated. We show that the experimental results agree well with those of the theoretical expectations. This study is the first report that a laser-generated SAW phase velocity dispersion technique is applied to soft materials. This technique may open a way for laser ultrasonics to detect the mechanical properties of soft tissues, such as skin.

© 2011 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(240.6690) Optics at surfaces : Surface waves
(350.5030) Other areas of optics : Phase
(280.3375) Remote sensing and sensors : Laser induced ultrasonics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 16, 2011
Revised Manuscript: April 10, 2011
Manuscript Accepted: April 11, 2011
Published: May 9, 2011

Virtual Issues
Vol. 6, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Chunhui Li, Zhihong Huang, and Ruikang K. Wang, "Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry," Opt. Express 19, 10153-10163 (2011)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-19-11-10153


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References

  1. D. Schneider and T. A. Schwarz, “Photoacoustic method for characterising thin films,” Surf. Coat. Tech. 91(1-2), 136–146 (1997). [CrossRef]
  2. H. S. Wang, S. Fleming, S. Law, and T. Huang, “Selection of Appropriate Laser Parameters for Launching Surface Acoustic waves on Tooth Enamel for Non-Destructive hardness Measurement,” in Proceedings of IEEE Australian Conference of Optical Fibre Technology/Australian Optical Society (ACOFT/AOS), (2006).
  3. Q. J. Huang, Y. Cheng, X. J. Liu, X. D. Xu, and S. Y. Zhang, “Study of the elastic constants in a La0.6Sr0.4MnO3 film by means of laser-generated ultrasonic wave method,” Ultrasonics 44(Suppl 1), e1223–e1227 (2006). [CrossRef] [PubMed]
  4. F. Reverdy and B. Audoin, “Ultrasonic measurement of elastic constant of anisotropic materials with laser source and laser receiver focused on the same interface,” J. Appl. Phys. 90(9), 4829–4835 (2001). [CrossRef]
  5. P. Ridgway, R. Russo, E. Lafond, T. Jackson, and X. Zhang, “A Sensor for Laser Ultrasonic Measurement of Elastic Properties During Manufacture,” in Proceedings of 16th WCNDT 2004 - World Conference on NDT. (2004), paper 466.
  6. C. S. Scruby and L. E. Drain, Laser Ultrasonics: Techniques and Applications (1990).
  7. H. C. Wang, S. Fleming, Y. C. Lee, S. Law, M. Swain, and J. Xue, “Laser ultrasonic surface wave dispersion technique for non-destructive evaluation of human dental enamel,” Opt. Express 17(18), 15592–15607 (2009). [CrossRef] [PubMed]
  8. H. C. Wang, S. Fleming, and Y. C. Lee, “Simple, all-optical, noncontact, depth-selective, narrowband surface acoustic wave measurement system for evaluating the Rayleigh velocity of small samples or areas,” Appl. Opt. 48(8), 1444–1451 (2009). [CrossRef] [PubMed]
  9. A. L’Etang and Z. Y. Huang, “FE simulation of laser generated surface acoustic wave propagation in skin,” Ultrasonics 44(Suppl 1), e1243–e1247 (2006). [CrossRef] [PubMed]
  10. A. L’Etang and Z. Y. Huang, “FE simulation of laser ultrasonic surface waves in a biomaterial model,” Appl. Mech. Mater. 3–4, 85–90 (2005). [CrossRef]
  11. T. Kundu, ed., Ultrasonic nondestructive evaluation: engineering and biological material characterization (2004).
  12. D. Schneider, B. Schultrich, H. J. Scheibe, H. Ziegele, and M. Griepentrog, “A laser-acoustic method for testing and classifying hard surface layers,” Thin Solid Films 332(1–2), 157–163 (1998). [CrossRef]
  13. C. Glorieux, W. Gao, S. E. Kruger, K. Van de Rostyne, W. Lauriks, and J. Thoen, “Surface acoustic wave depth profiling of elastically inhomogeneous materials,” J. Appl. Phys. 88(7), 4394–4400 (2000). [CrossRef]
  14. J. A. Rogers, A. A. Maznev, M. J. Banet, and K. A. Nelson, “Optical generation and characterization of acoustic waves in thin films: fundamentals and applications,” Annu. Rev. Mater. Sci. 30(1), 117–157 (2000). [CrossRef]
  15. Y. C. Lee, J. O. Kim, and J. D. Achenbach, “Measurement of elastic constants and mass density by acoustic microscopy”, IEEE Ultrasonics Symposium, 1, 607–612 (1993).
  16. A. Neubrand and P. Hess, “Laser generation and detection of surface acoustic waves: Elastic properties of surface layers,” J. Appl. Phys. 71(1), 227–238 (1992). [CrossRef]
  17. D. H. Hurley and J. B. Spicer, “Line source representation for laser-generated ultrasound in an elastic transversely isotropic half-space,” J. Acoust. Soc. Am. 116(5), 2914–2922 (2004). [CrossRef]
  18. P. A. Doyle and C. M. Scala, “Near-field ultrasonic Rayleigh waves from a laser line source,” Ultrasonics 34(1), 1–8 (1996). [CrossRef]
  19. S. Kenderian, B. B. Djordjevic, and R. E. Green., “Point and Line Source Laser Generation of Ultrasound for Inspection of Internal and Surface Flaws in Rail and Structural Materials,” Res. Nondestruct. Eval. 13, 189–200 (2001).
  20. R. K. Wang and L. An, “Doppler optical micro-angiography for volumetric imaging of vascular perfusion in vivo,” Opt. Express 17(11), 8926–8940 (2009). [CrossRef] [PubMed]
  21. R. K. Wang and A. L. Nuttall, “Phase-sensitive optical coherence tomography imaging of the tissue motion within the organ of Corti at a subnanometer scale: a preliminary study,” J. Biomed. Opt. 15(5), 056005 (2010). [CrossRef] [PubMed]
  22. W. Sun, Y. Peng, and J. Xu, “A de-noising method for laser ultrasonic signal based on EMD,” J. Sandong Univ. 38(5), 1–6 (2008).
  23. T. Terada and C. Tsubio, “Experimental studies on elastic waves Part I,” A manuscript of the Earthquake Research Institute, Japan.
  24. T. Nitta, H. Haga, K. Kawabata, K. Abe, and T. Sambongi, “Comparing microscopic with macroscopic elastic properties of polymer gel,” Ultramicroscopy 82(1-4), 223–226 (2000). [CrossRef] [PubMed]
  25. T. Z. Pavan, E. L. Madsen, G. R. Frank, A. Adilton O Carneiro, and T. J. Hall, “Nonlinear elastic behavior of phantom materials for elastography,” Phys. Med. Biol. 55(9), 2679–2692 (2010). [CrossRef] [PubMed]

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