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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 19, Iss. 13 — Jun. 20, 2011
  • pp: 11932–11943

Iterative reconstruction of projection images from a microlens-based optical detector

Liji Cao and Jörg Peter  »View Author Affiliations

Optics Express, Vol. 19, Issue 13, pp. 11932-11943 (2011)

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A microlens-based optical detector was developed to perform small animal optical imaging. In this paper we present an iterative reconstruction algorithm yielding improved image quality and spatial resolution as compared to conventional inverse mapping. The reconstruction method utilizes the compressive sensing concept to cope with the undersampling nature of the problem. Each iteration in the algorithm contains two separate steps to ensure both the convergence of the least-square solution and the minimization of the l1-norm of the sparsifying transform. The results estimated from measurements, employing a Derenzo-like pattern and a Siemens star phantom, illustrate significant improvements in contrast and spatial resolution in comparison to results calculated by inverse mapping.

© 2011 OSA

OCIS Codes
(080.0080) Geometric optics : Geometric optics
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3010) Medical optics and biotechnology : Image reconstruction techniques

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: February 14, 2011
Revised Manuscript: April 13, 2011
Manuscript Accepted: April 14, 2011
Published: June 6, 2011

Virtual Issues
Vol. 6, Iss. 7 Virtual Journal for Biomedical Optics

Liji Cao and Jörg Peter, "Iterative reconstruction of projection images from a microlens-based optical detector," Opt. Express 19, 11932-11943 (2011)

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