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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 19, Iss. 5 — Feb. 28, 2011
  • pp: 4157–4169

Scanning ophthalmoscope retinal image registration using one-dimensional deformation fields

S. Faisan, D. Lara, and C. Paterson  »View Author Affiliations


Optics Express, Vol. 19, Issue 5, pp. 4157-4169 (2011)
http://dx.doi.org/10.1364/OE.19.004157


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Abstract

We present a new, robust and automated method for registering sequences of images acquired from scanning ophthalmoscopes. The method uses a multi-scale B-spline representation of the deformation field to map images to each other and an hierarchical optimization method. We applied the method to video sequences acquired from different parts of the retina. In all cases, the registration was successful, even in the presence of large distortions from microsaccades, and the resulting deformation fields describe the fixational motion of the eye. The registration reveals examples of dynamic photoreceptor behaviour in the sequences.

© 2011 Optical Society of America

OCIS Codes
(100.0100) Image processing : Image processing
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.5810) Medical optics and biotechnology : Scanning microscopy
(170.5755) Medical optics and biotechnology : Retina scanning

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 8, 2010
Revised Manuscript: December 17, 2010
Manuscript Accepted: December 19, 2010
Published: February 17, 2011

Virtual Issues
Vol. 6, Iss. 3 Virtual Journal for Biomedical Optics

Citation
S. Faisan, D. Lara, and C. Paterson, "Scanning ophthalmoscope retinal image registration using one-dimensional deformation fields," Opt. Express 19, 4157-4169 (2011)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-19-5-4157


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References

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