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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 19, Iss. 9 — Apr. 25, 2011
  • pp: 8879–8887

Path-length resolved reflectance in tendon and muscle

Chuanmao Fan, Ali Shuaib, and Gang Yao  »View Author Affiliations

Optics Express, Vol. 19, Issue 9, pp. 8879-8887 (2011)

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Optical diffuse reflectance in fibrous tissues depends on measurement angles in relation to fiber orientation. In this study, path-length resolved optical reflectance was measured in tendon and skeletal muscle samples using a low-coherence Mach-Zehnder interferometer. The results show that the angular dependency in reflectance was eliminated in tendon tissue when representing reflectance as a function of mean path-length. Our analysis indicated that this observation can be understood in the frame work of anisotropic diffuse theory. However the same phenomenon was not observed in muscles, suggesting involvement of additional scattering mechanisms.

© 2011 OSA

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(290.1350) Scattering : Backscattering
(290.1990) Scattering : Diffusion
(290.7050) Scattering : Turbid media

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: February 9, 2011
Revised Manuscript: April 10, 2011
Manuscript Accepted: April 11, 2011
Published: April 22, 2011

Virtual Issues
Vol. 6, Iss. 5 Virtual Journal for Biomedical Optics

Chuanmao Fan, Ali Shuaib, and Gang Yao, "Path-length resolved reflectance in tendon and muscle," Opt. Express 19, 8879-8887 (2011)

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  1. T. J. Farrell, M. S. Patterson, and B. C. Wilson, “A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the non-invasive determination of tissue optical properties in vivo,” Med. Phys. 19(4), 879–888 (1992). [CrossRef] [PubMed]
  2. A. Kienle, F. K. Forster, and R. Hibst, “Anisotropy of light propagation in biological tissue,” Opt. Lett. 29(22), 2617–2619 (2004). [CrossRef] [PubMed]
  3. A. Kienle, F. K. Forster, R. Diebolder, and R. Hibst, “Light propagation in dentin: influence of microstructure on anisotropy,” Phys. Med. Biol. 48(2), N7–N14 (2003). [CrossRef] [PubMed]
  4. S. Nickell, M. Hermann, M. Essenpreis, T. J. Farrell, U. Krämer, and M. S. Patterson, “Anisotropy of light propagation in human skin,” Phys. Med. Biol. 45(10), 2873–2886 (2000). [CrossRef] [PubMed]
  5. J. Ranasinghesagara and G. Yao, “Imaging 2D optical diffuse reflectance in skeletal muscle,” Opt. Express 15(7), 3998–4007 (2007), http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-7-3998 . [CrossRef] [PubMed]
  6. A. Kienle, C. Wetzel, A. Bassi, D. Comelli, P. Taroni, and A. Pifferi, “Determination of the optical properties of anisotropic biological media using an isotropic diffusion model,” J. Biomed. Opt. 12(1), 014026 (2007). [CrossRef] [PubMed]
  7. P. M. Johnson, B. P. J. Bret, J. G. Rivas, J. J. Kelly, and A. Lagendijk, “Anisotropic diffusion of light in a strongly scattering material,” Phys. Rev. Lett. 89(24), 243901 (2002). [CrossRef] [PubMed]
  8. O. K. Dudko, G. H. Weiss, V. Chernomordik, and A. H. Gandjbakhche, “Photon migration in turbid media with anisotropic optical properties,” Phys. Med. Biol. 49(17), 3979–3989 (2004). [CrossRef] [PubMed]
  9. J. C. Hebden, J. J. G. Guerrero, V. Chernomordik, and A. H. Gandjbakhche, “Experimental evaluation of an anisotropic scattering model of a slab geometry,” Opt. Lett. 29(21), 2518–2520 (2004). [CrossRef] [PubMed]
  10. A. Sviridov, V. Chernomordik, M. Hassan, A. Russo, A. Eidsath, P. Smith, and A. H. Gandjbakhche, “Intensity profiles of linearly polarized light backscattered from skin and tissue-like phantoms,” J. Biomed. Opt. 10(1), 014012–014019 (2005). [CrossRef]
  11. J. Ranasinghesagara, F. Hsieh, and G. Yao, “A photon migration method for characterizing fiber formation in meat analogs,” J. Food Sci. 71(5), E227–E231 (2006). [CrossRef]
  12. R. L. Lieber, Skeletal Muscle Structure, Function & Plasticity: The Physiological Basis of Rehabilitation, 2nd ed. (Lippincott Williams & Wilkins, Philadelphia, 2002), p. 369.
  13. N. G. Laing and K. J. Nowak, “When contractile proteins go bad: the sarcomere and skeletal muscle disease,” Bioessays 27(8), 809–822 (2005). [CrossRef] [PubMed]
  14. J. Xia, A. Weaver, D. E. Gerrard, and G. Yao, “Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance,” J. Biomed. Opt. 11(4), 040504 (2006). [CrossRef] [PubMed]
  15. J. Ranasinghesagara and G. Yao, “Effects of inhomogeneous myofibril morphology on optical diffraction in single muscle fibers,” J. Opt. Soc. Am. A 25(12), 3051–3058 (2008). [CrossRef]
  16. J. Ranasinghesagara, T. M. Nath, S. J. Wells, A. D. Weaver, D. E. Gerrard, and G. Yao, “Imaging optical diffuse reflectance in beef muscles for tenderness prediction,” Meat Sci. 84(3), 413–421 (2010). [CrossRef] [PubMed]
  17. D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys. Med. Biol. 33(12), 1433–1442 (1988). [CrossRef] [PubMed]
  18. G. Popescu and A. Dogariu, “Optical path-length spectroscopy of wave propagation in random media,” Opt. Lett. 24(7), 442–444 (1999). [CrossRef]
  19. B. Varghese, V. Rajan, T. G. Van Leeuwen, and W. Steenbergen, “Path-length-resolved measurements of multiple scattered photons in static and dynamic turbid media using phase-modulated low-coherence interferometry,” J. Biomed. Opt. 12(2), 024020–024027 (2007). [CrossRef] [PubMed]
  20. M. A. Choma, C. Yang, and J. A. Izatt, “Instantaneous quadrature low-coherence interferometry with 3×3 fiber-optic couplers,” Opt. Lett. 28(22), 2162–2164 (2003). [CrossRef] [PubMed]
  21. A. Kienle and M. S. Patterson, “Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium,” J. Opt. Soc. Am. A 14(1), 246–254 (1997). [CrossRef]
  22. A. Shuaib and G. Yao, “Equi-intensity distribution of optical reflectance in a fibrous turbid medium,” Appl. Opt. 49(5), 838–844 (2010). [CrossRef] [PubMed]
  23. J. Xia and G. Yao, “Angular distribution of diffuse reflectance in biological tissue,” Appl. Opt. 46(26), 6552–6560 (2007). [CrossRef] [PubMed]

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