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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 2, Iss. 6 — Mar. 16, 1998
  • pp: 227–236

Three-dimensional reconstructions from low-count SPECT data using deformable models

G.S. Cunningham, K.M. Hanson, and X.L. Battle  »View Author Affiliations

Optics Express, Vol. 2, Issue 6, pp. 227-236 (1998)

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We demonstrate the reconstruction of a 3D, time-varying bolus of radiotracer from first-pass data obtained by the dynamic SPECT imager, FASTSPECT, built by the University of Arizona. The object imaged is a CardioWest Total Artificial Heart. The bolus is entirely contained in one ventricle and its associated inlet and outlet tubes. The model for the radiotracer distribution is a time-varying closed surface parameterized by 162 vertices that are connected to make 960 triangles, with uniform intensity of radiotracer inside. The total curvature of the surface is minimized through the use of a weighted prior in the Bayesian framework. MAP estimates for the vertices, interior intensity and background count level are produced for diastolic and systolic frames, the only two frames analyzed. The strength of the prior is determined by finding the corner of the L-curve. The results indicate that qualitatively pleasing results are possible even with as few as 1780 counts per time frame (total after summing over all 24 detectors). Quantitative estimates of ejection fraction and wall motion should be possible if certain restrictions in the model are removed, e.g., the spatial homogeneity of the radiotracer intensity within the volume defined by the triangulated surface, and smoothness of the surface at the tube/ventricle join.

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OCIS Codes
(100.3010) Image processing : Image reconstruction techniques
(110.6960) Imaging systems : Tomography

ToC Category:
Focus Issue: Tomographic image reconstruction

Original Manuscript: December 9, 1997
Published: March 16, 1998

Gregory Cunningham, Kenneth Hanson, and X. Battle, "Three-dimensional reconstructions from low-count SPECT data using deformable models," Opt. Express 2, 227-236 (1998)

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