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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 2 — Jan. 16, 2012
  • pp: 1237–1246

3D-visual laser-diode-based photoacoustic imaging

Lvming Zeng, Guodong Liu, Diwu Yang, and Xuanrong Ji  »View Author Affiliations

Optics Express, Vol. 20, Issue 2, pp. 1237-1246 (2012)

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We present a 3D-visual laser-diode-based photoacoustic imaging (LD-PAI) system with a pulsed semiconductor laser source, which has the properties of being inexpensive, portable, and durable. The laser source was operated at a wavelength of 905 nm with a repetition rate of 0.8 KHz. The energy density on the sample surface is about 2.35 mJ/cm2 with a pulse energy as low as 5.6 μJ. By raster-scanning, preliminary 3D volumetric renderings of the knotted and helical blood vessel phantoms have been visualized integrally with an axial resolution of 1.1 mm and a lateral resolution of 0.5 mm, and typical 2D photoacoustic image slices with different thickness and orientation were produced with clarity for detailed comparison and analysis in 3D diagnostic visualization. In addition, the pulsed laser source was integrated with the optical lens group and the 3D adjustable rotational stage, with the result that the compact volume of the total radiation source is only 10 × 3 × 3 cm3. Our goal is to significantly reduce the costs and sizes of the deep 3D-visual PAI system for future producibility.

© 2012 OSA

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.0110) Medical optics and biotechnology : Imaging systems

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: November 2, 2011
Revised Manuscript: December 12, 2011
Manuscript Accepted: December 23, 2011
Published: January 5, 2012

Virtual Issues
Vol. 7, Iss. 3 Virtual Journal for Biomedical Optics

Lvming Zeng, Guodong Liu, Diwu Yang, and Xuanrong Ji, "3D-visual laser-diode-based photoacoustic imaging," Opt. Express 20, 1237-1246 (2012)

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