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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 22 — Oct. 22, 2012
  • pp: 24115–24123

Exploiting few mode-fibers for optical time-stretch confocal microscopy in the short near-infrared window

Yi Qiu, Jingjiang Xu, Kenneth K. Y. Wong, and Kevin K. Tsia  »View Author Affiliations


Optics Express, Vol. 20, Issue 22, pp. 24115-24123 (2012)
http://dx.doi.org/10.1364/OE.20.024115


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Abstract

Dispersive fiber is well-regarded as the most viable candidate for realizing efficient optical time-stretch process – an ultrafast spectroscopic measurement technique based on the wavelength-to-time mapping via group velocity dispersion (GVD). Despite optical time-stretch has been anticipated to benefit a wide range of high-throughput biomedical diagnoses, the lack of commercially-available dispersive fibers which can operate in the “biomedically-favorable” short near-infrared (~800 nm – 1100 nm) range hinders practical time-stretch-based biomedical spectroscopy and microscopy. We here explore and demonstrate the feasibility of using the standard telecommunication single-mode fibers (e.g. SMF28 and dispersion compensation fiber (DCF)) as few-mode fibers (FMFs) for optical time-stretch confocal microscopy in the 1μm range. By evaluating GVD of different FMF modes and thus the corresponding time-stretch performances, we show that the fundamental modes (LP01) of SMF28 and DCF, having sufficiently high dispersion-to-loss ratios, are particularly useful for practical time-stretch spectroscopy and microscopy at 1 μm, without the need for the specialty 1 μm SMF. More intriguingly, we also show that the higher-order FMF modes (e.g. LP11) could be excited and utilized for time-stretch imaging. Such additional degree of freedom creates a new avenue for optimizing and designing the time-stretch operations, such as by tailored engineering of the modal-dispersion as well as the GVD of the individual FMF modes.

© 2012 OSA

OCIS Codes
(060.2350) Fiber optics and optical communications : Fiber optics imaging
(170.0110) Medical optics and biotechnology : Imaging systems
(170.0180) Medical optics and biotechnology : Microscopy
(170.7160) Medical optics and biotechnology : Ultrafast technology
(180.0180) Microscopy : Microscopy

ToC Category:
Microscopy

History
Original Manuscript: July 13, 2012
Revised Manuscript: September 15, 2012
Manuscript Accepted: September 16, 2012
Published: October 8, 2012

Citation
Yi Qiu, Jingjiang Xu, Kenneth K. Y. Wong, and Kevin K. Tsia, "Exploiting few mode-fibers for optical time-stretch confocal microscopy in the short near-infrared window," Opt. Express 20, 24115-24123 (2012)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-20-22-24115


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References

  1. D. R. Solli, J. Chou, and B. Jalali, “Amplified wavelength-time transformation for real-time spectroscopy,” Nat. Photonics2(1), 48–51 (2008). [CrossRef]
  2. K. Goda, D. R. Solli, K. Tsia, and B. Jalali, “Theory of amplified dispersive Fourier transformation,” Phys. Rev. A80(4), 043821 (2009). [CrossRef]
  3. J. Chou, D. R. Solli, and B. Jalali, “Real-time spectroscopy with subgigahertz resolution using amplified dispersive Fourier transformation,” Appl. Phys. Lett.92(11), 111102 (2008). [CrossRef]
  4. S. Moon and D. Y. Kim, “Ultra-high-speed optical coherence tomography with a stretched pulse supercontinuum source,” Opt. Express14(24), 11575–11584 (2006). [CrossRef] [PubMed]
  5. T.-J. Ahn, Y. Park, and J. Azaña, “Ultrarapid optical frequency-domain reflectometry based upon dispersion-induced time stretching: principle and applications,” IEEE J. Sel. Top. Quantum Electron.18(1), 148–165 (2012). [CrossRef]
  6. K. Goda, K. K. Tsia, and B. Jalali, “Amplified dispersive Fourier-transform imaging for ultrafast displacement sensing and barcode reading,” Appl. Phys. Lett.93(13), 131109 (2008). [CrossRef]
  7. A. M. Fard, A. Mahjoubfar, K. Goda, D. R. Gossett, D. Di Carlo, and B. Jalali, “Nomarski serial time-encoded amplified microscopy for high-speed contrast-enhanced imaging of transparent media,” Biomed. Opt. Express2(12), 3387–3392 (2011). [CrossRef] [PubMed]
  8. K. K. Tsia, K. Goda, D. Capewell, and B. Jalali, “Performance of serial time-encoded amplified microscope,” Opt. Express18(10), 10016–10028 (2010). [CrossRef] [PubMed]
  9. K. Goda, K. K. Tsia, and B. Jalali, “Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena,” Nature458(7242), 1145–1149 (2009). [CrossRef] [PubMed]
  10. C. Zhang, Y. Qiu, R. Zhu, K. K. Y. Wong, and K. K. Tsia, “Serial time-encoded amplified microscopy based on picosecond supercontinuum source,” Opt. Express19, 15810–15816 (2011). [CrossRef] [PubMed]
  11. T.-J. Ahn, Y. Jung, K. Oh, and D. Y. Kim, “Optical frequency-domain chromatic dispersion measurement method for higher-order modes in an optical fiber,” Opt. Express13(25), 10040–10048 (2005). [CrossRef] [PubMed]
  12. F. Yaman, N. Bai, B. Zhu, T. Wang, and G. Li, “Long distance transmission in few-mode fibers,” Opt. Express18(12), 13250–13257 (2010). [CrossRef] [PubMed]
  13. F. Yaman, N. Bai, Y. K. Huang, M. F. Huang, B. Zhu, T. Wang, and G. Li, “10 x 112Gb/s PDM-QPSK transmission over 5032 km in few-mode fibers,” Opt. Express18(20), 21342–21349 (2010). [CrossRef] [PubMed]
  14. S. Ramachandran, “Dispersion-tailored few-mode Fibers: A versatile platform for in-fiber photonic devices,” J. Lightwave Technol.23(11), 3426–3443 (2005). [CrossRef]
  15. T. T. W. Wong, A. K. S. Lau, K. K. Y. Wong, and K. K. Tsia, “Optical time-stretch confocal microscopy at 1um,” Opt. Lett.37(16), 3330–3332 (2012). [CrossRef]
  16. K. Goda, A. Mahjoubfar, C. Wang, A. Fard, J. Adam, D. R. Gossett, A. Ayazi, E. Sollier, O. Malik, E. Chen, Y. Liu, R. Brown, N. Sarkhosh, D. Di Carlo, and B. Jalali, “Hybrid dispersion laser Scanner,” Sci Rep2(445), 1–8 (2012). [PubMed]
  17. P. Hamel, Y. Jaouën, R. Gabet, and S. Ramachandran, “Optical low-coherence reflectometry for complete chromatic dispersion characterization of few-mode fibers,” Opt. Lett.32(9), 1029–1031 (2007). [CrossRef] [PubMed]
  18. S. Ramachandran, Fiber Based Dispersion Compensation, 1st ed. (Springer, 2007).
  19. A. F. Zuluaga, R. Drezek, T. Collier, R. Lotan, M. Follen, and R. Richards-Kortum, “Contrast agents for confocal microscopy: how simple chemicals affect confocal images of normal and cancer cells in suspension,” J. Biomed. Opt.7(3), 398–403 (2002). [CrossRef] [PubMed]
  20. D. Yelin, C. Boudoux, B. E. Bouma, and G. J. Tearney, “Large area confocal microscopy,” Opt. Lett.32(9), 1102–1104 (2007). [CrossRef] [PubMed]
  21. K. K. Tsia, K. Goda, D. Capewell, and B. Jalali, “Simultaneous mechanical-scan-free confocal microscopy and laser microsurgery,” Opt. Lett.34(14), 2099–2101 (2009). [CrossRef] [PubMed]
  22. C. Boudoux, S. Yun, W. Oh, W. White, N. Iftimia, M. Shishkov, B. Bouma, and G. Tearney, “Rapid wavelength-swept spectrally encoded confocal microscopy,” Opt. Express13(20), 8214–8221 (2005). [CrossRef] [PubMed]

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