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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 3 — Jan. 30, 2012
  • pp: 3353–3366

Automated phase retardation oriented segmentation of chorio-scleral interface by polarization sensitive optical coherence tomography

Lian Duan, Masahiro Yamanari, and Yoshiaki Yasuno  »View Author Affiliations

Optics Express, Vol. 20, Issue 3, pp. 3353-3366 (2012)

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An automated chorio-scleral interface (CSI) detection algorithm based on polarization sensitive optical coherence tomography (PS-OCT) is presented. This algorithm employs a two-step scheme based on the phase retardation variation detected by PS-OCT. In the first step, a rough CSI segmentation is implemented to distinguish the choroid and sclera by using depth-oriented second derivative of the phase retardation. Second, the CSI is further finely defined as the intersection of lines fitted to the phase retardation in the choroid and sclera. This algorithm challenges the current back-scattering intensity based CSI segmentation approaches that are not fully based on anatomical and morphological evidence, and provides a rational segmentation method for the morphological investigation of the choroid. Applications of this algorithm are demonstrated on in vivo posterior images acquired by a PS-OCT system with 1-μm probe.

© 2012 OSA

OCIS Codes
(100.2960) Image processing : Image analysis
(110.4500) Imaging systems : Optical coherence tomography
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: December 22, 2011
Revised Manuscript: January 18, 2012
Manuscript Accepted: January 19, 2012
Published: January 27, 2012

Virtual Issues
Vol. 7, Iss. 3 Virtual Journal for Biomedical Optics

Lian Duan, Masahiro Yamanari, and Yoshiaki Yasuno, "Automated phase retardation oriented segmentation of chorio-scleral interface by polarization sensitive optical coherence tomography," Opt. Express 20, 3353-3366 (2012)

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