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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 4 — Feb. 13, 2012
  • pp: 4805–4811

Easily fabricated, robust fiber-optic probe for weak fluorescence detection: modeling and initial experimental evaluation

Jianjun Ma, Yasser Chiniforooshan, Wenhui Hao, Wojtek J. Bock, and Zhi Yuan Wang  »View Author Affiliations

Optics Express, Vol. 20, Issue 4, pp. 4805-4811 (2012)

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Detection of fluorescence from a low quantum yield fluorophore is challenging for a fiber-optic probe, especially when an inexpensive and robust construction is desired. We propose a conceptually straightforward theoretical model to optimize the factors affecting the fluorescence-capture capability of a bifurcated/coaxial fiber-optic probe. Experimentally we verify that such a probe, if optimized, can detect the fluorescence of a polymer fluorophore with a low quantum yield of 0.0065.

© 2012 OSA

OCIS Codes
(060.2270) Fiber optics and optical communications : Fiber characterization
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(300.6280) Spectroscopy : Spectroscopy, fluorescence and luminescence

ToC Category:

Original Manuscript: January 26, 2012
Manuscript Accepted: February 2, 2012
Published: February 10, 2012

Virtual Issues
Vol. 7, Iss. 4 Virtual Journal for Biomedical Optics

Jianjun Ma, Yasser Chiniforooshan, Wenhui Hao, Wojtek J. Bock, and Zhi Yuan Wang, "Easily fabricated, robust fiber-optic probe for weak fluorescence detection: modeling and initial experimental evaluation," Opt. Express 20, 4805-4811 (2012)

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  1. B. A. Flusberg, E. D. Cocker, W. Piyawattanametha, J. C. Jung, E. L. M. Cheung, and M. J. Schnitzer, “Fiber-optic fluorescence imaging,” Nat. Methods 2(12), 941–950 (2005). [CrossRef] [PubMed]
  2. M. G. Shim, B. C. Wilson, E. Marple, and M. Wach, “Study of fiber-optic probes for in vivo medical Raman spectroscopy,” Appl. Spectrosc. 53(6), 619–627 (1999). [CrossRef]
  3. L. Wen-xu and C. Jian, “Continuous monitoring of adriamycin in vivo using fiber optic-based fluorescence chemical sensor,” Anal. Chem. 75(6), 1458–1462 (2003). [CrossRef] [PubMed]
  4. T. F. Coony, H. T. Skinner, and S. M. Angel, “Comparative study of some fiber-optic remote Raman probe designs. Part I: model for liquids and transparent solids,” Appl. Spectrosc. 50(7), 836–848 (1996). [CrossRef]
  5. U. Bunting, F. Lewitzka, and P. Karlitschek, “Mathematical model of a laser-induced fluorescence fiber-optic sensor head for trace detection of pollutants in soil,” Appl. Spectrosc. 53(1), 49–56 (1999). [CrossRef]
  6. K. R. Rogers and E. J. Poziomek, “Fiber optic sensors for environmental monitoring,” Chemosphere 33(6), 1151–1174 (1996). [CrossRef]
  7. J. Ma and W. Bock, “Modeling of photonic crystal fiber with air holes sealed at the fiber end and its application to fluorescent light collection efficiency enhancement,” Opt. Express 13(7), 2385–2393 (2005). [CrossRef] [PubMed]
  8. X. B. Zhang, C. C. Guo, Z. Z. Li, G. L. Shen, and R. Q. Yu, “An optical fiber chemical sensor for mercury ions based on a porphyrin dimer,” Anal. Chem. 74(4), 821–825 (2002). [CrossRef] [PubMed]

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