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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 21, Iss. 13 — Jul. 1, 2013
  • pp: 15298–15307

Spatial-spectral coupling in coherent anti-Stokes Raman scattering microscopy

Aaron M. Barlow, Konstantin Popov, Marco Andreana, Douglas J. Moffatt, Andrew Ridsdale, Aaron D. Slepkov, James L. Harden, Lora Ramunno, and Albert Stolow  »View Author Affiliations

Optics Express, Vol. 21, Issue 13, pp. 15298-15307 (2013)

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Coherent anti-Stokes Raman scattering (CARS) microscopy is a third-order nonlinear optical technique which permits label-free, molecule-specific hyperspectral imaging. The interference between coherent resonant and non-resonant terms leads to well known distortions in the vibrational spectrum, requiring the use of retrieval algorithms. It also leads to spatial imaging distortions, largely due to the Gouy phase, when objects are smaller than the Rayleigh range. Here we consider that the focal position and spectral contributions to the nonlinear image formation are intrinsically coupled and cannot be corrected by conventional retrieval methods.

© 2013 OSA

OCIS Codes
(020.3690) Atomic and molecular physics : Line shapes and shifts
(030.1670) Coherence and statistical optics : Coherent optical effects
(300.6230) Spectroscopy : Spectroscopy, coherent anti-Stokes Raman scattering
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:

Original Manuscript: April 30, 2013
Manuscript Accepted: June 9, 2013
Published: June 19, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Aaron M. Barlow, Konstantin Popov, Marco Andreana, Douglas J. Moffatt, Andrew Ridsdale, Aaron D. Slepkov, James L. Harden, Lora Ramunno, and Albert Stolow, "Spatial-spectral coupling in coherent anti-Stokes Raman scattering microscopy," Opt. Express 21, 15298-15307 (2013)

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