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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 21, Iss. 19 — Sep. 23, 2013
  • pp: 22854–22861

Multi-channel deep tissue flowmetry based on temporal diffuse speckle contrast analysis

Renzhe Bi, Jing Dong, and Kijoon Lee  »View Author Affiliations

Optics Express, Vol. 21, Issue 19, pp. 22854-22861 (2013)

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Recently, diffuse speckle contrast analysis (DSCA) was introduced as a competent modality for deep tissue blood flow measurement, where the speckle contrast is calculated over spatial domain on the CCD image of diffuse reflectance. In this paper, we introduce time-domain DSCA where temporal statistics are used for speckle contrast calculation and results in the same deep tissue flow measurement. This new modality is especially suitable for multi-channel real-time flowmetry, and we demonstrate its performance on human arm during cuff occlusion test. Independent component analysis (ICA) study on multi-channel data shows promising results about underlying physiology.

© 2013 OSA

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(290.1990) Scattering : Diffusion

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 12, 2013
Revised Manuscript: August 10, 2013
Manuscript Accepted: September 6, 2013
Published: September 20, 2013

Virtual Issues
Vol. 8, Iss. 10 Virtual Journal for Biomedical Optics

Renzhe Bi, Jing Dong, and Kijoon Lee, "Multi-channel deep tissue flowmetry based on temporal diffuse speckle contrast analysis," Opt. Express 21, 22854-22861 (2013)

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