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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 21, Iss. 23 — Nov. 18, 2013
  • pp: 28062–28071

Portable spherical array probe for volumetric real-time optoacoustic imaging at centimeter-scale depths

X. Luís Deán-Ben and Daniel Razansky  »View Author Affiliations


Optics Express, Vol. 21, Issue 23, pp. 28062-28071 (2013)
http://dx.doi.org/10.1364/OE.21.028062


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Abstract

We report on a novel hand-held imaging probe for real-time optoacoustic visualization of deep tissues in three dimensions. The system incorporates an annular two-dimensional array of ultrasonic sensors densely distributed on a spherical surface. Simultaneous recording and processing of time-resolved data from all the channels enables acquisition of entire volumetric data sets for each illumination laser pulse. The proposed solution utilizes a transparent membrane in order to allow efficient coupling of optoacoustically generated waves to the ultrasonic detectors while avoiding direct contact of the imaged object with the coupling medium. The hand-held approach further allows convenient handling of both pre-clinical experiments as well as clinical measurements in human subjects. Here we demonstrate an imaging speed of 10 volumetric frames per second with spatial resolution down to 200 micrometers in the imaged region while also achieving imaging depth of more than 1.5 cm in living tissues without signal averaging.

© 2013 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(110.6955) Imaging systems : Tomographic imaging

ToC Category:
Imaging Systems

History
Original Manuscript: June 5, 2013
Revised Manuscript: July 11, 2013
Manuscript Accepted: July 11, 2013
Published: November 8, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Citation
X. Luís Deán-Ben and Daniel Razansky, "Portable spherical array probe for volumetric real-time optoacoustic imaging at centimeter-scale depths," Opt. Express 21, 28062-28071 (2013)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-21-23-28062


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