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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 21, Iss. 24 — Dec. 2, 2013
  • pp: 29792–29807

A dual-modal retinal imaging system with adaptive optics

Alexander Meadway, Christopher A. Girkin, and Yuhua Zhang  »View Author Affiliations


Optics Express, Vol. 21, Issue 24, pp. 29792-29807 (2013)
http://dx.doi.org/10.1364/OE.21.029792


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Abstract

An adaptive optics scanning laser ophthalmoscope (AO-SLO) is adapted to provide optical coherence tomography (OCT) imaging. The AO-SLO function is unchanged. The system uses the same light source, scanning optics, and adaptive optics in both imaging modes. The result is a dual-modal system that can acquire retinal images in both en face and cross-section planes at the single cell level. A new spectral shaping method is developed to reduce the large sidelobes in the coherence profile of the OCT imaging when a non-ideal source is used with a minimal introduction of noise. The technique uses a combination of two existing digital techniques. The thickness and position of the traditionally named inner segment/outer segment junction are measured from individual photoreceptors. In-vivo images of healthy and diseased human retinas are demonstrated.

© 2013 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(110.1080) Imaging systems : Active or adaptive optics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 23, 2013
Revised Manuscript: November 1, 2013
Manuscript Accepted: November 12, 2013
Published: November 25, 2013

Virtual Issues
Vol. 9, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Alexander Meadway, Christopher A. Girkin, and Yuhua Zhang, "A dual-modal retinal imaging system with adaptive optics," Opt. Express 21, 29792-29807 (2013)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-21-24-29792


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