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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 21, Iss. 25 — Dec. 16, 2013
  • pp: 30183–30195

Comparison of two x-ray phase-contrast imaging methods with a microfocus source

T. Zhou, U. Lundström, T. Thüring, S. Rutishauser, D. H. Larsson, M. Stampanoni, C. David, H. M. Hertz, and A. Burvall  »View Author Affiliations

Optics Express, Vol. 21, Issue 25, pp. 30183-30195 (2013)

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We present a comparison for high-resolution imaging with a laboratory source between grating-based (GBI) and propagation-based (PBI) x-ray phase-contrast imaging. The comparison is done through simulations and experiments using a liquid-metal-jet x-ray microfocus source. Radiation doses required for detection in projection images are simulated as a function of the diameter of a cylindrical sample. Using monochromatic radiation, simulations show a lower dose requirement for PBI for small object features and a lower dose for GBI for larger object features. Using polychromatic radiation, such as that from a laboratory microfocus source, experiments and simulations show a lower dose requirement for PBI for a large range of feature sizes. Tested on a biological sample, GBI shows higher noise levels than PBI, but its advantage of quantitative refractive index reconstruction for multi-material samples becomes apparent.

© 2013 Optical Society of America

OCIS Codes
(110.2960) Imaging systems : Image analysis
(110.6760) Imaging systems : Talbot and self-imaging effects
(110.7440) Imaging systems : X-ray imaging

ToC Category:
X-ray Optics

Original Manuscript: September 25, 2013
Revised Manuscript: November 12, 2013
Manuscript Accepted: November 22, 2013
Published: December 2, 2013

Virtual Issues
Vol. 9, Iss. 2 Virtual Journal for Biomedical Optics

T. Zhou, U. Lundström, T. Thüring, S. Rutishauser, D. H. Larsson, M. Stampanoni, C. David, H. M. Hertz, and A. Burvall, "Comparison of two x-ray phase-contrast imaging methods with a microfocus source," Opt. Express 21, 30183-30195 (2013)

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