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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 22, Iss. 15 — Jul. 28, 2014
  • pp: 18724–18735

Ultrafast 2D IR microscopy

Carlos R. Baiz, Denise Schach, and Andrei Tokmakoff  »View Author Affiliations

Optics Express, Vol. 22, Issue 15, pp. 18724-18735 (2014)

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We describe a microscope for measuring two-dimensional infrared (2D IR) spectra of heterogeneous samples with μm-scale spatial resolution, sub-picosecond time resolution, and the molecular structure information of 2D IR, enabling the measurement of vibrational dynamics through correlations in frequency, time, and space. The setup is based on a fully collinear “one beam” geometry in which all pulses propagate along the same optics. Polarization, chopping, and phase cycling are used to isolate the 2D IR signals of interest. In addition, we demonstrate the use of vibrational lifetime as a contrast agent for imaging microscopic variations in molecular environments.

© 2014 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(300.0300) Spectroscopy : Spectroscopy
(300.6340) Spectroscopy : Spectroscopy, infrared
(300.6530) Spectroscopy : Spectroscopy, ultrafast
(320.5540) Ultrafast optics : Pulse shaping
(180.4315) Microscopy : Nonlinear microscopy

ToC Category:

Original Manuscript: June 13, 2014
Revised Manuscript: July 16, 2014
Manuscript Accepted: July 16, 2014
Published: July 25, 2014

Virtual Issues
Vol. 9, Iss. 9 Virtual Journal for Biomedical Optics

Carlos R. Baiz, Denise Schach, and Andrei Tokmakoff, "Ultrafast 2D IR microscopy," Opt. Express 22, 18724-18735 (2014)

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