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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 22, Iss. 5 — Mar. 10, 2014
  • pp: 5731–5745

Noise suppressed optical diffraction tomography with autofocus correction

Julianna Kostencka, Tomasz Kozacki, Michał Dudek, and Małgorzata Kujawińska  »View Author Affiliations

Optics Express, Vol. 22, Issue 5, pp. 5731-5745 (2014)

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We propose a novel tomographic measurement approach that enables a noise suppressed characterization of microstructures. The idea of this work is based on a finding that coherent noise in the input phase data generates an artificial circular structure whose magnitude is the highest at the centre of tomographic reconstruction. This method decreases the noise level by applying an unconventional tomographic measurement configuration with an object deliberately shifted with respect to the rotation axis. This enables a spatial separation between the reconstructed sample structure and the area of the largest refractive index perturbations. The input phase data defocusing that is a by-product of the introduced modification is numerically corrected with an automatic focus correction algorithm. The proposed method is validated with simulations and experimental measurements of an optical microtip.

© 2014 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(110.6960) Imaging systems : Tomography
(180.6900) Microscopy : Three-dimensional microscopy
(090.1995) Holography : Digital holography

ToC Category:
Imaging Systems

Original Manuscript: September 25, 2013
Revised Manuscript: January 14, 2014
Manuscript Accepted: January 14, 2014
Published: March 5, 2014

Virtual Issues
Vol. 9, Iss. 5 Virtual Journal for Biomedical Optics

Julianna Kostencka, Tomasz Kozacki, Michał Dudek, and Małgorzata Kujawińska, "Noise suppressed optical diffraction tomography with autofocus correction," Opt. Express 22, 5731-5745 (2014)

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