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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 22, Iss. 7 — Apr. 7, 2014
  • pp: 7399–7415

High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes

Barry Vuong, Anthony M.D. Lee, Timothy W.H. Luk, Cuiru Sun, Stephen Lam, Pierre Lane, and Victor X.D. Yang  »View Author Affiliations


Optics Express, Vol. 22, Issue 7, pp. 7399-7415 (2014)
http://dx.doi.org/10.1364/OE.22.007399


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Abstract

We report a technique for blood flow detection using split spectrum Doppler optical coherence tomography (ssDOCT) that shows improved sensitivity over existing Doppler OCT methods. In ssDOCT, the Doppler signal is averaged over multiple sub-bands of the interferogram, increasing the SNR of the Doppler signal. We explore the parameterization of this technique in terms of number of sub-band windows, width and overlap of the windows, and their effect on the Doppler signal to noise in a flow phantom. Compared to conventional DOCT, ssDOCT processing has increased flow sensitivity. We demonstrate the effectiveness of ssDOCT in-vivo for intravascular flow detection within a porcine carotid artery and for microvascular vessel detection in human pulmonary imaging, using rotary catheter probes. To our knowledge, this is the first report of visualizing in-vivo Doppler flow patterns adjacent to stent struts in the carotid artery.

© 2014 Optical Society of America

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 3, 2014
Revised Manuscript: March 10, 2014
Manuscript Accepted: March 12, 2014
Published: March 24, 2014

Virtual Issues
Vol. 9, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Barry Vuong, Anthony M.D. Lee, Timothy W.H. Luk, Cuiru Sun, Stephen Lam, Pierre Lane, and Victor X.D. Yang, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes," Opt. Express 22, 7399-7415 (2014)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-22-7-7399


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